Archive for the ‘ophthalmic anti-inflammatory agents’ Category

Xibrom

Xibrom

Generic Name: bromfenac (ophthalmic) (BROM fen ak)

What is Xibrom?

Xibrom is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the production of prostaglandin, a substance that causes inflammation (redness, swelling, irritation).

Xibrom is an eye drop useded to treat eye pain and swelling in patients who have recently had surgery to remove cataracts. This medicine is available only with your doctor’s prescription.

Xibrom may also be used for other purposes not listed here.

Important information about Xibrom

Use this medication exactly as it was prescribed for you. Do not use it in larger doses or for longer than recommended by your doctor. Follow the directions on your prescription label.

Before using this medication, tell your doctor if you are pregnant or breast-feeding.

If you miss a dose, use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

Before using Xibrom tell your doctor if you are using a steroid such as prednisone, dexamethasone, or others. You may not be able to use Xibrom or you may need dosage adjustments or special tests during treatment.

Stop using this medication and get emergency medical help if you think you have used too much medicine, or if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects are more likely, and you may have none at all. Talk to your doctor about any side effect that seems unusual or is especially bothersome.

Before using Xibrom

You should not use this medication if you have ever had an allergic reaction to bromfenac.

Before using Xibrom, tell your doctor if you are allergic to any drugs, or if you have:

asthma;

diabetes;

rheumatoid arthritis;

dry eye syndrome;

a drug allergy;

a bleeding disorder; or

more than one eye surgery in a short period of time.

If you have any of these conditions, you may need a dose adjustment or special tests to safely use Xibrom.

FDA pregnancy category C: This medication may be harmful to an unborn baby. Do not use Xibrom without telling your doctor if you are pregnant. Tell your doctor if you become pregnant during treatment. It is not known if Xibrom passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use Xibrom?

Use Xibrom exactly as it was prescribed for you. Do not use it in larger doses or for longer than recommended by your doctor. Follow the directions on your prescription label.

Wash your hands before using the eye drops.

If you wear contact lenses, remove them before applying Xibrom. Ask your doctor if contact lenses can be reinserted after putting in the eye drops. Xibrom may contain a preservative (benzalkonium chloride) that can cause discoloration of contact lenses.

To apply the eye drops:

Tilt your head back slightly and pull down on the lower eyelid to create a small pocket. Hold the dropper above the eye with the dropper tip down. Look up and away from the dropper. Squeeze out a drop and close your eye. Gently press your finger to the inside corner of the eye (near the nose) for about 1 minute to keep the liquid from draining into your tear duct. If you use more than one drop in the same eye, wait about 5 minutes before putting in the next drop.

Xibrom is usually used two times a day for 14 days. Follow your doctor’s directions.

Do not touch the dropper to any surface, including the eyes or hands. If the dropper becomes contaminated, it could cause an infection in your eye. Store the drops at room temperature away from heat and moisture. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine, or if anyone has accidentally swallowed it. An overdose of this medication is unlikely to be harmful.

What should I avoid while taking Xibrom?

Xibrom can cause side effects that may impair your vision. Be careful if you drive or do anything that requires you to be able to see clearly. Avoid using other medications in your eyes during treatment with Xibrom unless your doctor has told you to.

Xibrom side effects

Stop using Xibrom and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Xibrom and call your doctor at once if you have any change in your vision.

Other less serious side effects are more likely to occur, such as:

feeling like something is in your eye;

eye pain, itching, or redness; or

headache.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Xibrom?

Before using Xibrom tell your doctor if you are using a steroid such as prednisone, dexamethasone, and others.

This list is not complete and there may be other drugs that can interact with Xibrom Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Xibrom

Xibrom

Generic Name: bromfenac (ophthalmic) (BROM fen ak)

What is Xibrom?

Xibrom is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the production of prostaglandin, a substance that causes inflammation (redness, swelling, irritation).

Xibrom is an eye drop useded to treat eye pain and swelling in patients who have recently had surgery to remove cataracts. This medicine is available only with your doctor’s prescription.

Xibrom may also be used for other purposes not listed here.

Important information about Xibrom

Use this medication exactly as it was prescribed for you. Do not use it in larger doses or for longer than recommended by your doctor. Follow the directions on your prescription label.

Before using this medication, tell your doctor if you are pregnant or breast-feeding.

If you miss a dose, use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

Before using Xibrom tell your doctor if you are using a steroid such as prednisone, dexamethasone, or others. You may not be able to use Xibrom or you may need dosage adjustments or special tests during treatment.

Stop using this medication and get emergency medical help if you think you have used too much medicine, or if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects are more likely, and you may have none at all. Talk to your doctor about any side effect that seems unusual or is especially bothersome.

Before using Xibrom

You should not use this medication if you have ever had an allergic reaction to bromfenac.

Before using Xibrom, tell your doctor if you are allergic to any drugs, or if you have:

asthma;

diabetes;

rheumatoid arthritis;

dry eye syndrome;

a drug allergy;

a bleeding disorder; or

more than one eye surgery in a short period of time.

If you have any of these conditions, you may need a dose adjustment or special tests to safely use Xibrom.

FDA pregnancy category C: This medication may be harmful to an unborn baby. Do not use Xibrom without telling your doctor if you are pregnant. Tell your doctor if you become pregnant during treatment. It is not known if Xibrom passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use Xibrom?

Use Xibrom exactly as it was prescribed for you. Do not use it in larger doses or for longer than recommended by your doctor. Follow the directions on your prescription label.

Wash your hands before using the eye drops.

If you wear contact lenses, remove them before applying Xibrom. Ask your doctor if contact lenses can be reinserted after putting in the eye drops. Xibrom may contain a preservative (benzalkonium chloride) that can cause discoloration of contact lenses.

To apply the eye drops:

Tilt your head back slightly and pull down on the lower eyelid to create a small pocket. Hold the dropper above the eye with the dropper tip down. Look up and away from the dropper. Squeeze out a drop and close your eye. Gently press your finger to the inside corner of the eye (near the nose) for about 1 minute to keep the liquid from draining into your tear duct. If you use more than one drop in the same eye, wait about 5 minutes before putting in the next drop.

Xibrom is usually used two times a day for 14 days. Follow your doctor’s directions.

Do not touch the dropper to any surface, including the eyes or hands. If the dropper becomes contaminated, it could cause an infection in your eye. Store the drops at room temperature away from heat and moisture. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine, or if anyone has accidentally swallowed it. An overdose of this medication is unlikely to be harmful.

What should I avoid while taking Xibrom?

Xibrom can cause side effects that may impair your vision. Be careful if you drive or do anything that requires you to be able to see clearly. Avoid using other medications in your eyes during treatment with Xibrom unless your doctor has told you to.

Xibrom side effects

Stop using Xibrom and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Xibrom and call your doctor at once if you have any change in your vision.

Other less serious side effects are more likely to occur, such as:

feeling like something is in your eye;

eye pain, itching, or redness; or

headache.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Xibrom?

Before using Xibrom tell your doctor if you are using a steroid such as prednisone, dexamethasone, and others.

This list is not complete and there may be other drugs that can interact with Xibrom Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Voltaren Ophthalmic

Voltaren Drops

Voltaren Drops are used for:

Treating pain, redness, swelling, and sensitivity to light, which are symptoms related to certain eye surgeries. It may also be used for other conditions as determined by your doctor.

Voltaren Drops are a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing chemicals in the body that cause pain and inflammation.

Do NOT use Voltaren Drops if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Voltaren Drops:

Some medical conditions may interact with Voltaren Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Voltaren Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Voltaren Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Voltaren Drops:

Use Voltaren Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Voltaren Drops.

Important safety information:

Possible side effects of Voltaren Drops:

All medicines may cause side effects, but many people have no, or minor, side effects.

Burning or stinging; discharge; eye redness, irritation, or itching.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred or distorted vision; eye infection; eyelid swelling or redness; sensitivity to glare or light; severe or persistent eye irritation.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Store Voltaren Drops at room temperature, between 59 and 77 degrees F (15 and 25 degrees C), in the original container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Voltaren Drops out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Voltaren Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Voltaren Drops resources

Compare Voltaren Drops with other medications for the treatment of:

Voltaren Ophthalmic

Voltaren Drops

Voltaren Drops are used for:

Treating pain, redness, swelling, and sensitivity to light, which are symptoms related to certain eye surgeries. It may also be used for other conditions as determined by your doctor.

Voltaren Drops are a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing chemicals in the body that cause pain and inflammation.

Do NOT use Voltaren Drops if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Voltaren Drops:

Some medical conditions may interact with Voltaren Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Voltaren Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Voltaren Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Voltaren Drops:

Use Voltaren Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Voltaren Drops.

Important safety information:

Possible side effects of Voltaren Drops:

All medicines may cause side effects, but many people have no, or minor, side effects.

Burning or stinging; discharge; eye redness, irritation, or itching.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred or distorted vision; eye infection; eyelid swelling or redness; sensitivity to glare or light; severe or persistent eye irritation.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Store Voltaren Drops at room temperature, between 59 and 77 degrees F (15 and 25 degrees C), in the original container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Voltaren Drops out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Voltaren Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Voltaren Drops resources

Compare Voltaren Drops with other medications for the treatment of:

Trivaris

Trivaris

Generic Name: triamcinolone acetonide

FDA Approves Trivaris

The U.S. Food and Drug Administration (FDA) has approved Trivaris (triamcinolone acetonide injectable suspension) 80 mg/mL, a synthetic glucocorticoid corticosteroid with anti-inflammatory action. Delivered via intravitreal injection, the ophthalmic indications for Trivaris include sympathetic ophthalmia, temporal arteritis, uveitis, and ocular inflammatory conditions unresponsive to topical corticosteroids. These are inflammatory conditions that can result in vision loss.

Important Safety Information

Prolonged use of corticosteroids may produce posterior subcapsular cataracts, glaucoma with possible damage to the optic nerves, and may enhance the establishment of secondary ocular infections.

The use of oral corticosteroids is not recommended in the treatment of optic neuritis and may lead to an increase in the risk of new episodes.

Intraocular pressure may become elevated in some individuals. If steroid therapy is continued for more than 6 weeks, intraocular pressure should be monitored.

Corticosteroids should be used cautiously in patients with a history of ocular herpes simplex because of possible corneal perforation. Corticosteroids should not be used in active ocular herpes simplex.

Highlights of Trivaris Prescribing Information

These highlights do not include all the information needed to use Trivaris (triamcinolone acetonide injectable suspension) 80 mg/mL safely and effectively. See full prescribing information for Trivaris.

Indications and Usage

Trivaris is a corticosteroid indicated for:

Dosage and Administration

Dosage Forms and Strengths

Contraindications

Warnings and Precautions

To report SUSPECTED ADVERSE REACTIONS, contact Allergan at 1-800-433-8871 or www.allergan.com or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Drug Interactions

NSAIDS including aspirin and salicylates: Increased risk of gastrointestinal side effects.

Patient Counseling Information

Patients should discuss with their physician if they have had recent or ongoing infections or if they have recently received a vaccine.

There are a number of medicines that can interact with corticosteroids such as triamcinolone. Patients should inform their health-care provider of all the medicines they are taking, including over-the counter and prescription medicines (such as phenytoin, diuretics, digitalis or digoxin, rifampin, amphotericin B, cyclosporine, insulin or diabetes medicines, ketoconazole, estrogens including birth control pills and hormone replacement therapy, blood thinners such as warfarin, aspirin or other NSAIDS, barbiturates), dietary supplements, and herbal products. If patients are taking any of these drugs, alternate therapy, dosage adjustment, and/or special test may be needed during the treatment.

Patients should be advised of common adverse reactions that could occur with corticosteroid use to include elevated intraocular pressure, cataracts, fluid retention, alteration in glucose tolerance, elevation in blood pressure, behavioral and mood changes, increased appetite and weight gain.

In the days following intravitreal administration of Trivaris, patients are at risk for the development of endophthalmitis. If the eye becomes red, sensitive to light, painful or develops a change in vision, the patients should seek immediate care from an ophthalmologist.

For more information, please see

More Trivaris resources

Trivaris

Trivaris

Generic Name: triamcinolone acetonide

FDA Approves Trivaris

The U.S. Food and Drug Administration (FDA) has approved Trivaris (triamcinolone acetonide injectable suspension) 80 mg/mL, a synthetic glucocorticoid corticosteroid with anti-inflammatory action. Delivered via intravitreal injection, the ophthalmic indications for Trivaris include sympathetic ophthalmia, temporal arteritis, uveitis, and ocular inflammatory conditions unresponsive to topical corticosteroids. These are inflammatory conditions that can result in vision loss.

Important Safety Information

Prolonged use of corticosteroids may produce posterior subcapsular cataracts, glaucoma with possible damage to the optic nerves, and may enhance the establishment of secondary ocular infections.

The use of oral corticosteroids is not recommended in the treatment of optic neuritis and may lead to an increase in the risk of new episodes.

Intraocular pressure may become elevated in some individuals. If steroid therapy is continued for more than 6 weeks, intraocular pressure should be monitored.

Corticosteroids should be used cautiously in patients with a history of ocular herpes simplex because of possible corneal perforation. Corticosteroids should not be used in active ocular herpes simplex.

Highlights of Trivaris Prescribing Information

These highlights do not include all the information needed to use Trivaris (triamcinolone acetonide injectable suspension) 80 mg/mL safely and effectively. See full prescribing information for Trivaris.

Indications and Usage

Trivaris is a corticosteroid indicated for:

Dosage and Administration

Dosage Forms and Strengths

Contraindications

Warnings and Precautions

To report SUSPECTED ADVERSE REACTIONS, contact Allergan at 1-800-433-8871 or www.allergan.com or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Drug Interactions

NSAIDS including aspirin and salicylates: Increased risk of gastrointestinal side effects.

Patient Counseling Information

Patients should discuss with their physician if they have had recent or ongoing infections or if they have recently received a vaccine.

There are a number of medicines that can interact with corticosteroids such as triamcinolone. Patients should inform their health-care provider of all the medicines they are taking, including over-the counter and prescription medicines (such as phenytoin, diuretics, digitalis or digoxin, rifampin, amphotericin B, cyclosporine, insulin or diabetes medicines, ketoconazole, estrogens including birth control pills and hormone replacement therapy, blood thinners such as warfarin, aspirin or other NSAIDS, barbiturates), dietary supplements, and herbal products. If patients are taking any of these drugs, alternate therapy, dosage adjustment, and/or special test may be needed during the treatment.

Patients should be advised of common adverse reactions that could occur with corticosteroid use to include elevated intraocular pressure, cataracts, fluid retention, alteration in glucose tolerance, elevation in blood pressure, behavioral and mood changes, increased appetite and weight gain.

In the days following intravitreal administration of Trivaris, patients are at risk for the development of endophthalmitis. If the eye becomes red, sensitive to light, painful or develops a change in vision, the patients should seek immediate care from an ophthalmologist.

For more information, please see

More Trivaris resources

Triesence

Triesence

Generic Name: triamcinolone (ophthalmic) (trye am SIN oh lone off THAL mik)

What is Triesence?

Triesence contains triamcinolone, a corticosteroid. It prevents the release of substances in the body that cause inflammation.

Triesence is injected into the eye to treat inflammation caused by disease or injury. It is usually given after steroid eye drops have been used without successful treatment of symptoms.

Triesence is also used during a certain type of eye surgery (vitrectomy).

Triesence may also be used for other purposes not listed in this medication guide.

Important information about Triesence

You should not receive Triesence if you are allergic to triamcinolone, or if you have a fungal infection anywhere in your body. Do not use Triesence without telling your doctor if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

Before receiving Triesence, tell your doctor if you have any type of bacterial, fungal, or viral infection (including tuberculosis). Also tell your doctor if you have cataracts or glaucoma, herpes infection of your eye, diabetes, high blood pressure, congestive heart failure, a thyroid disorder, myasthenia gravis, a stomach or intestinal disorder, or a history of recent heart attack.

Before you receive any vaccine, talk with the doctor who is treating you with Triesence. Some vaccines may not work as well or could cause harmful side effects during treatment with steroid medicine.

Steroids can lower the blood cells that help your body fight infections Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles.

There are many other medicines that can interact with Triesence. Tell your doctor about all the prescription and over-the-counter medications you use. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

What should I discuss with my health care provider before receiving Triesence?

You should not receive Triesence if you are allergic to triamcinolone, or if you have a fungal infection anywhere in your body.

If you have certain conditions, you may need a dose adjustment or special tests to safely receive this medication. Before receiving Triesence, tell your doctor if you are allergic to any drugs, or if you have:

herpes infection of your eye;

eye conditions such as cataract or glaucoma;

diabetes;

high blood pressure, congestive heart failure;

any type of bacterial, fungal, or viral infection (including tuberculosis);

a thyroid disorder;

a muscle disorder such as myasthenia gravis;

diverticulitis, stomach or intestinal ulcer, or recent stomach surgery; or

if you have recently had a heart attack.

FDA pregnancy category D. Triesence can cause harm to an unborn baby or cause birth defects. Before you receive Triesence, tell your doctor if you are pregnant. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment. Triamcinolone can pass into breast milk and may harm a nursing baby. Do not receive Triesence without telling your doctor if you are breast-feeding a baby.

This medication can decrease bone formation, which could lead to osteoporosis, especially with long-term use. Talk with your doctor about your specific risk of bone loss while receiving Triesence.

Steroids can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

How is Triesence given?

Triesence is given as an injection into your eye. Your doctor will use a medicine to numb your eye before giving you the injection. You will receive this injection in your doctor’s office or other clinic setting.

For at least 30 minutes after your Triesence injection, your eyes will be checked periodically to make sure the injection has not caused any side effects.

Long-term use of steroids can cause harmful effects on the eyes, such as glaucoma or cataracts. If you receive Triesence for longer than 6 weeks, your doctor may want you to have regular eye exams.

Steroids can lower the blood cells that help your body fight infections. This can make it easier for you to get sick from being around others who are ill, or from bacteria in a skin wound. Steroids can also slow the healing of skin wounds. Use caution to prevent illness, infection, or injury.

Your doctor may instruct you to limit your salt intake while you are receiving Triesence. You may also need to take potassium supplements. Follow your doctor’s instructions.

Triesence can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are being treated with Triesence.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your injection.

What happens if I overdose?

Seek emergency medical attention if you think you have received too much of this medicine.

Since this medication is given by a healthcare professional, an overdose is unlikely to occur.

What should I avoid while receiving Triesence?

Do not receive a smallpox vaccine or any other “live” vaccine if you are being treated long-term with Triesence. Some vaccines may not work as well during treatment with steroid medicine at certain doses. Some vaccines may even cause dangerous side effects when used during steroid treatment. Before you receive any vaccine, talk with the doctor who is treating you with Triesence.

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroids.

Triesence side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Triesence: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

problems with your vision, blurred vision, or seeing halos around lights;

eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection);

large red or purple spots on your skin;

fast, slow, or uneven heart rate;

feeling short of breath, swelling in your hands or feet;

increased blood pressure (severe headache, blurred vision, chest pain, shortness of breath, uneven heartbeats);

ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes;

severe depression, changes in mood or behavior, seizures (convulsions); or

severe pain in your upper stomach.

Less serious Triesence side effects may include:

mild eye discomfort;

headaches, back aches, weakness, confusion;

bloating, appetite changes, weight gain;

changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist), roundness in your face, ;

increased acne or facial hair;

menstrual problems (in women), impotence or loss of interest in sex (in men);

dry skin, thinning skin, changes in skin color;

bruising, sweating more than usual; or

a wound that is slow to heal.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Triesence?

Many drugs can interact with triamcinolone (Triesence). Below is just a partial list. Tell your doctor if you are using:

amphotericin B (Fungizone, AmBisome, Abelcet);

birth control pills or hormone replacement therapy;

a blood thinner such as warfarin (Coumadin);

cholestyramine (Prevalite, Questran);

cyclosporine (Neoral, Gengraf, Sandimmune);

digoxin (digitalis, Lanoxin);

a diuretic (water pill);

insulin or diabetes medications you take by mouth;

isoniazid (for treating tuberculosis);

rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin);

an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin) or telithromycin (Ketek);

an antifungal medication such as itraconazole (Sporanox), ketoconazole (Nizoral), or voriconazole (Vfend);

aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), piroxicam (Feldene), and others;

heart or blood pressure medication such as diltiazem (Cardizem, Dilacor, Tiazac), quinidine (Quinaglute, Quinidex, Quin-Release), or verapamil (Calan, Covera, Isoptin, Verelan);

HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), efavirenz (Sustiva), fosamprenavir (Lexiva), indinavir (Crixivan), nevirapine (Viramune), saquinavir (Invirase, Fortovase), ritonavir (Norvir), and others;

medications to treat dementia, such as donepezil (Aricept), rivastigmine (Exelon), galantamine (Razadyne), tacrine (Cognex); or

seizure medication such as carbamazepine (Carbatrol, Tegretol), phenobarbital (Solfoton), phenytoin (Dilantin), and others.

This list is not complete and there are many other medicines that can interact with Triesence. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Triesence

Triesence

Generic Name: triamcinolone (ophthalmic) (trye am SIN oh lone off THAL mik)

What is Triesence?

Triesence contains triamcinolone, a corticosteroid. It prevents the release of substances in the body that cause inflammation.

Triesence is injected into the eye to treat inflammation caused by disease or injury. It is usually given after steroid eye drops have been used without successful treatment of symptoms.

Triesence is also used during a certain type of eye surgery (vitrectomy).

Triesence may also be used for other purposes not listed in this medication guide.

Important information about Triesence

You should not receive Triesence if you are allergic to triamcinolone, or if you have a fungal infection anywhere in your body. Do not use Triesence without telling your doctor if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

Before receiving Triesence, tell your doctor if you have any type of bacterial, fungal, or viral infection (including tuberculosis). Also tell your doctor if you have cataracts or glaucoma, herpes infection of your eye, diabetes, high blood pressure, congestive heart failure, a thyroid disorder, myasthenia gravis, a stomach or intestinal disorder, or a history of recent heart attack.

Before you receive any vaccine, talk with the doctor who is treating you with Triesence. Some vaccines may not work as well or could cause harmful side effects during treatment with steroid medicine.

Steroids can lower the blood cells that help your body fight infections Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles.

There are many other medicines that can interact with Triesence. Tell your doctor about all the prescription and over-the-counter medications you use. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

What should I discuss with my health care provider before receiving Triesence?

You should not receive Triesence if you are allergic to triamcinolone, or if you have a fungal infection anywhere in your body.

If you have certain conditions, you may need a dose adjustment or special tests to safely receive this medication. Before receiving Triesence, tell your doctor if you are allergic to any drugs, or if you have:

herpes infection of your eye;

eye conditions such as cataract or glaucoma;

diabetes;

high blood pressure, congestive heart failure;

any type of bacterial, fungal, or viral infection (including tuberculosis);

a thyroid disorder;

a muscle disorder such as myasthenia gravis;

diverticulitis, stomach or intestinal ulcer, or recent stomach surgery; or

if you have recently had a heart attack.

FDA pregnancy category D. Triesence can cause harm to an unborn baby or cause birth defects. Before you receive Triesence, tell your doctor if you are pregnant. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment. Triamcinolone can pass into breast milk and may harm a nursing baby. Do not receive Triesence without telling your doctor if you are breast-feeding a baby.

This medication can decrease bone formation, which could lead to osteoporosis, especially with long-term use. Talk with your doctor about your specific risk of bone loss while receiving Triesence.

Steroids can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

How is Triesence given?

Triesence is given as an injection into your eye. Your doctor will use a medicine to numb your eye before giving you the injection. You will receive this injection in your doctor’s office or other clinic setting.

For at least 30 minutes after your Triesence injection, your eyes will be checked periodically to make sure the injection has not caused any side effects.

Long-term use of steroids can cause harmful effects on the eyes, such as glaucoma or cataracts. If you receive Triesence for longer than 6 weeks, your doctor may want you to have regular eye exams.

Steroids can lower the blood cells that help your body fight infections. This can make it easier for you to get sick from being around others who are ill, or from bacteria in a skin wound. Steroids can also slow the healing of skin wounds. Use caution to prevent illness, infection, or injury.

Your doctor may instruct you to limit your salt intake while you are receiving Triesence. You may also need to take potassium supplements. Follow your doctor’s instructions.

Triesence can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are being treated with Triesence.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your injection.

What happens if I overdose?

Seek emergency medical attention if you think you have received too much of this medicine.

Since this medication is given by a healthcare professional, an overdose is unlikely to occur.

What should I avoid while receiving Triesence?

Do not receive a smallpox vaccine or any other “live” vaccine if you are being treated long-term with Triesence. Some vaccines may not work as well during treatment with steroid medicine at certain doses. Some vaccines may even cause dangerous side effects when used during steroid treatment. Before you receive any vaccine, talk with the doctor who is treating you with Triesence.

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroids.

Triesence side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Triesence: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

problems with your vision, blurred vision, or seeing halos around lights;

eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection);

large red or purple spots on your skin;

fast, slow, or uneven heart rate;

feeling short of breath, swelling in your hands or feet;

increased blood pressure (severe headache, blurred vision, chest pain, shortness of breath, uneven heartbeats);

ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes;

severe depression, changes in mood or behavior, seizures (convulsions); or

severe pain in your upper stomach.

Less serious Triesence side effects may include:

mild eye discomfort;

headaches, back aches, weakness, confusion;

bloating, appetite changes, weight gain;

changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist), roundness in your face, ;

increased acne or facial hair;

menstrual problems (in women), impotence or loss of interest in sex (in men);

dry skin, thinning skin, changes in skin color;

bruising, sweating more than usual; or

a wound that is slow to heal.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Triesence?

Many drugs can interact with triamcinolone (Triesence). Below is just a partial list. Tell your doctor if you are using:

amphotericin B (Fungizone, AmBisome, Abelcet);

birth control pills or hormone replacement therapy;

a blood thinner such as warfarin (Coumadin);

cholestyramine (Prevalite, Questran);

cyclosporine (Neoral, Gengraf, Sandimmune);

digoxin (digitalis, Lanoxin);

a diuretic (water pill);

insulin or diabetes medications you take by mouth;

isoniazid (for treating tuberculosis);

rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin);

an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin) or telithromycin (Ketek);

an antifungal medication such as itraconazole (Sporanox), ketoconazole (Nizoral), or voriconazole (Vfend);

aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), piroxicam (Feldene), and others;

heart or blood pressure medication such as diltiazem (Cardizem, Dilacor, Tiazac), quinidine (Quinaglute, Quinidex, Quin-Release), or verapamil (Calan, Covera, Isoptin, Verelan);

HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), efavirenz (Sustiva), fosamprenavir (Lexiva), indinavir (Crixivan), nevirapine (Viramune), saquinavir (Invirase, Fortovase), ritonavir (Norvir), and others;

medications to treat dementia, such as donepezil (Aricept), rivastigmine (Exelon), galantamine (Razadyne), tacrine (Cognex); or

seizure medication such as carbamazepine (Carbatrol, Tegretol), phenobarbital (Solfoton), phenytoin (Dilantin), and others.

This list is not complete and there are many other medicines that can interact with Triesence. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Restasis

Restasis

Generic Name: cyclosporine ophthalmic (sye kloe SPOR in off THAL mick)

What is Restasis?

Restasis (cyclosporine) is an immunosuppressive agent. Cyclosporine may reduce inflammation in the eye(s).

Restasis is used to treat chronic dry eye that may be caused by inflammation.

Restasis may also be used for purposes other than those listed in this medication guide.

Important information about Restasis

Do not touch the Restasis dropper on to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye(s).

Do not use Restasis while wearing contact lenses. Contact lenses may be reinserted 15 minutes following administration of Restasis, unless otherwise directed by your doctor.

What should I discuss with my healthcare provider before using Restasis?

Do not use Restasis if you have any type of infection in the eye(s). This medicine is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not use Restasis without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether cyclosporine passes into breast milk. Do not use Restasis without first talking to your doctor if you are breast-feeding a baby.

How should I use Restasis?

Use Restasis eye drops exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Wash your hands before using the eye drops.

To apply the eye drops:

Gently turn the bottle upside down a few times to obtain a uniformly white mixture in the bottle. Tilt your head back slightly and pull down on your lower eyelid. Position the dropper above your eye. Look up and away from the dropper. Squeeze out a drop and close your eye. Repeat the process in the other eye if directed.

Use Restasis twice a day, approximately every 12 hours, unless otherwise directed by your doctor.

Use each bottle for one dose only (one or both eyes). Throw away any remaining medication.

Artificial tears may be used during treatment with Restasis. Allow a 15 minute interval between application of the two products.

Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye(s).

Do not use Restasis while wearing contact lenses. Contact lenses may be reinserted 15 minutes following administration of Restasis, unless otherwise directed by your doctor.

Store this medicine at room temperature away from moisture and heat. Keep the bottle properly capped.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not use a double dose of the medication.

What happens if I overdose?

An overdose of Restasis is unlikely to occur. If you do suspect an overdose, wash the eye with water and call an emergency room or poison control center. If the drops have been ingested, call an emergency center for advice.

What should I avoid while using Restasis?

Do not use Restasis while wearing contact lenses. Contact lenses may be reinserted 15 minutes following administration, unless otherwise directed by your doctor.

Artificial tears may be used during treatment with this medicine. Allow a 15 minute interval between application of the two products. Do not use other eye drops or medications during treatment with Restasis unless otherwise directed by your doctor.

What are the possible side effects of Restasis?

Serious side effects are not expected to occur during treatment with Restasis.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Restasis?

Do not use other eye drops or medications during treatment with Restasis unless otherwise directed by your doctor.

Artificial tears may be used during treatment with Restasis. Allow a 15 minute interval between application of the two products.

Drugs other than those listed here may also interact with Restasis. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Profenal

Profenal

Generic Name: suprofen ophthalmic (SOO proe fin)

What is Profenal (suprofen ophthalmic)?

Suprofen is in a class of drugs called nonsteroidal anti-inflammatory drugs. It reduces pain and inflammation in the eyes.

Suprofen ophthalmic is used to prevent pupil constriction (reduced pupil size) during eye surgery.

Suprofen ophthalmic may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Profenal (suprofen ophthalmic)?

Do not touch the dropper to any surface, including your eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in your eye.

Apply light pressure to the inside corner of your eye (near your nose) after each drop to prevent the fluid from draining down your tear duct.

Who should not use Profenal (suprofen ophthalmic)?

Do not use suprofen ophthalmic if you have a herpes infection in your eye.

Before using suprofen ophthalmic, tell your doctor if you

have any type of bleeding or blood-clotting disease,

have recently had surgery, or

have stomach ulcers.

You may not be able to use suprofen ophthalmic, or you may require special monitoring during therapy if you have any of the conditions listed above.

Suprofen ophthalmic is in the FDA pregnancy category C. This means that it is not known whether suprofen ophthalmic will harm an unborn baby. Do not use this medication without first talking to your doctor if you are pregnant. It is also not known whether suprofen ophthalmic passes into breast milk. Do not use suprofen ophthalmic without first talking to your doctor if you are breast-feeding a baby.

How should I use Profenal (suprofen ophthalmic)?

Use suprofen eye drops exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Wash your hands before using the eyedrops.

To apply the eye drops:

Tilt your head back slightly and pull down on your lower eyelid. Position the dropper above your eye. Look up and away from the dropper. Squeeze out a drop and close your eye. Apply gentle pressure to the inside corner of your eye (near your nose) for about 1 minute to prevent the liquid from draining down your tear duct. If you are using more than one drop in the same eye or drops in both eyes, repeat the process with about 5 minutes between drops.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not use a double dose of this medication.

What happens if I overdose?

An overdose of this medication is unlikely to occur. If you do suspect an overdose, call an emergency room or poison control center near you. If the drops have been ingested, drink plenty of fluid and call an emergency center for advice.

What should I avoid while using Profenal (suprofen ophthalmic)?

Do not touch the dropper to any surface, including your eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in your eye. Use caution when driving, operating machinery, or performing other hazardous activities. Suprofen ophthalmic may cause blurred vision. If you experience blurred vision, avoid these activities.

If you wear contact lenses, ask your doctor if you should wear them during treatment with suprofen ophthalmic. After applying the medication, wait at least 15 minutes before inserting contact lenses, unless otherwise directed by your doctor.

Do not use other eye drops or medications during treatment with suprofen ophthalmic unless otherwise directed by your doctor.

Profenal (suprofen ophthalmic) side effects

Serious side effects are not expected with this medication.

Some eye burning, stinging, irritation, itching, redness, or sensitivity to light may occur. Continue to use suprofen ophthalmic and talk to your doctor about any side effects that you experience.

What other drugs will affect Profenal (suprofen ophthalmic)?

Do not use other eye drops or medications-especially acetylcholine chloride (Miochol) and carbachol (Carboptic, Isopto Carbachol), during treatment with suprofen ophthalmic unless otherwise directed by your doctor. These drugs may decrease the effects of suprofen ophthalmic.

Drugs other than those listed here may also interact with suprofen ophthalmic. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

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