Archive for the ‘atypical antipsychotics’ Category

FazaClo

Fazaclo

Generic Name: clozapine (KLOE za peen)

What is FazaClo?

FazaClo is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

FazaClo is used to treat severe schizophrenia symptoms in people who have not responded to other medications. FazaClo is also used to help reduce the risk of suicidal behavior in people with schizophrenia or similar disorders.

FazaClo may also be used for other purposes not listed in this medication guide.

Important information about FazaClo

FazaClo is not for use in psychotic conditions related to dementia. FazaClo may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions

You should not take FazaClo if you have uncontrolled epilepsy, paralytic ileus or intestinal blockage, an infection caused by FazaClo, or if you are also using drugs that weaken your immune system (such as cancer medicine or steroids).

While you are taking FazaClo, your blood may need to be tested every week for the first 6 months of treatment. Do not miss any scheduled blood tests.

Do not stop taking FazaClo or change your dose without first talking to your doctor.

Call your doctor if you have shortness of breath, swelling in your hands or feet, fever, weakness, sore throat, sudden numbness or weakness, sudden vision or speech problems, chest pain, cough, wheezing, pain or swelling in one or both legs, mouth sores, seizure, or jaundice (yellowing of your skin or eyes).

There are many other medicines that can interact with FazaClo. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Before taking FazaClo

FazaClo is not for use in psychotic conditions related to dementia. FazaClo may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions. You should not take this medication if you are allergic to clozapine, or if you have:

untreated or uncontrolled epilepsy;

paralytic ileus or intestinal blockage;

a history of infection while taking FazaClo; or

if you are also using drugs that weaken your immune system (such as cancer medicine or steroids).

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before taking FazaClo, tell your doctor if you have:

heart disease, heart rhythm disorder, high blood pressure, or a history of heart attack;

lung disease;

diabetes;

a history of bone marrow or blood cell disorders;

glaucoma; or

an enlarged prostate or urination problems.

FazaClo may raise your blood sugar, causing symptoms such as increased thirst, loss of appetite, increased urination, drowsiness, nausea, or fruity breath odor. Call your doctor right away if you have any of these symptoms.

FDA pregnancy category B: This medication is not expected to be harmful to an unborn baby. Do not use FazaClo without telling your doctor if you are pregnant or plan to become pregnant during treatment. FazaClo can pass into breast milk and may harm a nursing baby. You should not use this medication if you are breast-feeding a baby.

FazaClo orally-disintegrating tablets contain phenylalanine. Talk to your doctor before using FazaClo if you have phenylketonuria (PKU).

How should I take FazaClo?

Take FazaClo exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor. Follow the directions on your prescription label.

FazaClo can be taken with or without food.

The orally-disintegrating tablet (FazaClo) can be taken without water. Gently peel back the foil from the blister pack and drop the tablet onto your dry hand. Do not push tablet through the foil. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet.

If your doctor has prescribed one-half of an orally-disintegrating tablet, you will need to break the tablet in half. Throw the other half away. Do not store it for later use.

While you are taking FazaClo, your blood may need to be tested every week for the first 6 months of treatment. Do not miss any scheduled blood tests. After 6 months, blood tests may be needed less often.

If you stop taking FazaClo for more than 2 days in a row, call your doctor before you start taking it again. You may need a lower dose. Do not stop taking FazaClo or change your dose without first talking to your doctor. If you need to have any type of surgery, tell the surgeon ahead of time that you are using FazaClo. You may need to stop using the medicine for a short time. Store FazaClo at room temperature away from moisture and heat. Keep each FazaClo tablet in the unopened blister pack until you are ready to take the medicine.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include confusion, fast heart rate, drowsiness, drooling, weak or shallow breathing, feeling like you might pass out, and seizure (convulsions).

What should I avoid while taking FazaClo?

FazaClo may cause seizures, dizziness, or fainting. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of FazaClo.

FazaClo side effects

Stop using FazaClo and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

feeling short of breath, even at night or with mild exertion;

swelling in your hands or feet;

fever, weakness, sore throat, stiff muscles, confusion, sweating, fast or uneven heartbeats;

sudden numbness or weakness, especially on one side of the body;

sudden headache, confusion, problems with vision, speech, or balance;

chest pain, sudden cough, wheezing, rapid breathing, fast heart rate, pain or swelling in one or both legs;

white patches or sores inside your mouth or on your lips;

nausea, vomiting, loss of appetite, and jaundice (yellowing of your skin or eyes); or

seizure (black-out or convulsions).

Less serious side effects may include:

constipation;

drooling, especially at night;

increased sweating;

drowsiness, dizziness, spinning sensation;

sleep problems or nightmares; or

weight gain.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect FazaClo?

Before taking FazaClo, tell your doctor if you are using any of the following drugs:

cimetidine (Tagamet);

citalopram (Celexa);

lithium (Eskalith, Lithobid);

rifampin (Rifadin, Rimactane);

blood pressure medications;

heart rhythm medications such as propafenone (Rythmol) or flecaininde (Tambocor);

seizure medicine such as phenytoin (Dilantin) or carbamazepine (Carbatrol, Tegretol);

antibiotics such as ciprofloxacin (Cipro) or erythromycin (E-Mycin, E.E.S, Ery-Tab);

atropine (Donnatal, and others), belladonna, clidinium (Quarzan), dicyclomine (Bentyl), scopolamine (Transderm-Scop); or

diazepam (Valium) or similar medicines such as alprazolam (Xanax), clonazepam (Klonopin), lorazepam (Ativan), midazolam (Versed), temazepam (Restoril), and others.

This list is not complete and there may be other drugs that can interact with FazaClo. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Fanapt

Fanapt

Generic Name: iloperidone (EYE loe PER i done)

What is Fanapt?

Fanapt (iloperidone) is an antipsychotic medication. It works by changing the effects of chemicals in the brain.

Fanapt is used to treat schizophrenia.

Fanapt may also be used for other purposes not listed in this medication guide.

Important information about Fanapt

Fanapt is not for use in psychotic conditions related to dementia. Fanapt may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

Before using Fanapt, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Fanapt.

While you are taking Fanapt, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking this medicine.

Fanapt can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of Fanapt. Stop using this medicine and call your doctor at once if you have very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, restless muscle movements in your face or neck, tremor (uncontrolled shaking), trouble swallowing, or feeling like you might pass out.

If you have stopped taking Fanapt for any reason, talk with your doctor before you start taking it again. You may need to restart the medication at a lower dose.

Before taking Fanapt

Fanapt is not for use in psychotic conditions related to dementia. Iloperidone may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions. You should not use Fanapt if you are allergic to iloperidone.

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take Fanapt, tell your doctor if you have:

kidney or liver disease;

a personal or family history of Long QT syndrome;

seizures or epilepsy;

heart disease, high blood pressure, heart rhythm problems;

history of low white blood cell (WBC) counts;

a history of heart attack or stroke;

an electrolyte imbalance, such as low potassium or magnesium levels in your blood;

a history of breast cancer;

diabetes (Fanapt may raise your blood sugar);

trouble swallowing; or

a history of suicidal thoughts.

FDA pregnancy category C. It is not known whether Fanapt is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether iloperidone passes into breast milk or if it could harm a nursing baby. Do not use Fanapt without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from this medicine.

How should I take Fanapt?

Take Fanapt exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Fanapt can be taken with or without food.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments.

Fanapt may cause you to have high blood sugar (hyperglycemia). Talk to your doctor if you have any signs of hyperglycemia such as increased thirst or urination, excessive hunger, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking Fanapt.

If you have stopped taking Fanapt for any reason, talk with your doctor before you start taking it again. You may need to restart the medication at a lower dose.

Store this medicine at room temperature away from moisture, light, and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical treatment if you think you have used too much of this medicine.

Overdose symptoms may include drowsiness, fast heart rate, and feeling light-headed.

What should I avoid while taking Fanapt?

While you are taking Fanapt, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking Fanapt. This medicine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid drinking alcohol. It can increase some of the side effects of Fanapt.

Fanapt side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Fanapt: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking this medication and call your doctor at once if you have a serious side effect such as:

very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out;

twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;

tremor (uncontrolled shaking);

trouble swallowing;

seizure (convulsions);

urinating less than usual or not at all;

fever, chills, body aches, flu symptoms;

white patches or sores inside your mouth or in your lips;

feeling like you might pass out; or

penis erection that is painful or lasts 4 hours or longer.

Less serious Fanapt side effects may include:

dizziness, drowsiness, tired feeling;

dry mouth, stuffy nose, sore throat;

nausea, diarrhea, upset stomach;

joint pain;

breast swelling or discharge;

changes in menstrual periods;

blurred vision;

weight gain; or

mild skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Fanapt?

Before using Fanapt, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Fanapt.

The following drugs can interact with Fanapt. Tell your doctor if you are using any of these:

arsenic trioxide (Trisenox);

droperidol (Inapsine);

an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), ketoconazole (Nizoral), levofloxacin (Levaquin), moxifloxacin (Avelox), pentamidine (NebuPent, Pentam), rifampin (Rifadin, Rimactane, Rifater);

an antidepressant such as amitriptylline (Elavil, Vanatrip), clomipramine (Anafranil), desipramine (Norpramin), fluoxetine (Prozac, Sarafem), or paroxetine (Paxil);

anti-malaria medications such as chloroquine (Arelan), mefloquine (Lariam), or halofantrine (Halfan);

heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), ibutilide (Corvert), procainamide (Procan, Pronestyl), propafenone (Rythmol), quinidine (Quinidex, Quin-Release Quin-G), or sotalol (Betapace);

medicine to prevent or treat nausea and vomiting, such as dolasetron (Anzemet) or ondansetron (Zofran);

other medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon);

migraine headache medicine such as sumatriptan (Imitrex) or zolmitriptan (Zomig); or

narcotic medication such as levomethadyl (Orlaam), or methadone (Dolophine, Methadose).

This list is not complete and there may be other drugs that can interact with Fanapt. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Saphris

Saphris

Generic Name: asenapine (a SEN a peen)

What is Saphris?

Saphris is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

Saphris is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression) in adults.

Saphris may also be used for other purposes not listed in this medication guide.

Important information about Saphris

Saphris is not for use in psychotic conditions related to dementia. Saphris may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions. While you are taking Saphris, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking asenapine. Saphris can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Before taking Saphris, tell your doctor if you have liver disease, heart disease, high blood pressure, seizures, low white blood cell counts, diabetes, trouble swallowing, or a history of heart breast cancer, heart attack, stroke, or “Long QT syndrome.”

Avoid drinking alcohol, which can increase some of the side effects of Saphris. Stop taking Saphris and call your doctor at once if you have fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, restless muscle movements in your face or neck, tremor (uncontrolled shaking), trouble swallowing, feeling light-headed, or fainting.

Before taking Saphris

Saphris is not for use in psychotic conditions related to dementia. Saphris may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Saphris:

heart disease, high blood pressure, heart rhythm problems;

a history of heart attack or stroke;

a history of breast cancer;

seizures or epilepsy;

diabetes (asenapine may raise your blood sugar);

trouble swallowing;

Parkinson’s disease;

a history of low white blood cell (WBC) counts; or

a personal or family history of”Long QT syndrome.”

FDA pregnancy category C. It is not known whether Saphris is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. Asenapine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give Saphris to anyone younger than 18 years old without the advice of a doctor.

How should I take Saphris?

Take Saphris exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take this medicine with a full glass of water.

Saphris is usually taken 2 times per day. Follow your doctor’s instructions.

To take Saphris sublingual (under the tongue) tablets:

Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the colored tab from the tablet blister. Do not push a tablet through the blister or you may damage the tablet.

Using dry hands, gently remove the tablet and place it under your tongue. It will begin to dissolve right away.

Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

Swallow several times as the tablet dissolves. Do not eat or drink anything for 10 minutes after the tablet has dissolved.

Saphris may cause you to have high blood sugar (hyperglycemia). Symptoms include increased thirst, loss of appetite, increased urination, nausea, vomiting, drowsiness, dry skin, and dry mouth. If you are diabetic, check your blood sugar levels on a regular basis while you are taking Saphris.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments.

Store Saphris at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include agitation, confusion, and restless muscle movements in your eyes, tongue, jaw, or neck.

What should I avoid while taking Saphris?

While you are taking Saphris, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking this medication. Saphris can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid drinking alcohol, which can increase some of the side effects of Saphris.

Saphris side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Saphris: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Saphris and call your doctor at once if you have any of these serious side effects:

very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, feeling like you might pass out;

twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;

tremor (uncontrolled shaking);

trouble swallowing;

sudden numbness or weakness, especially on one side of the body;

sudden and severe headache, or problems with vision, speech, or balance;

easy bruising or bleeding, fever, chills, body aches, flu symptoms;

white patches or sores inside your mouth or on your lips;

seizure (convulsions); or

unusual thoughts or behavior, hallucinations, or thoughts about hurting yourself.

Less serious Saphris side effects may include:

dizziness, drowsiness;

restless feeling;

numbness or tingling inside or around your mouth;

constipation;

dry mouth;

sleep problems (insomnia);

upset stomach; or

weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Saphris?

Before using Saphris, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Saphris.

The following drugs can interact with Saphris. Tell your doctor if you are using

arsenic trioxide (Trisenox);

blood pressure medications;

droperidol (Inapsine);

an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), levofloxacin (Levaquin), moxifloxacin (Avelox), or pentamidine (NebuPent, Pentam);

an antidepressant such as amitriptylline (Elavil, Vanatrip), clomipramine (Anafranil), desipramine (Norpramin), fluoxetine (Prozac), or paroxetine (Paxil);

anti-malaria medications such as chloroquine (Arelan), or mefloquine (Lariam);

heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), ibutilide (Corvert), procainamide (Procan, Pronestyl), propafenone (Rythmol), quinidine (Quinidex, Quin-Release Quin-G), or sotalol (Betapace);

medicine to prevent or treat nausea and vomiting, such as dolasetron (Anzemet) or ondansetron (Zofran);

other medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon);

migraine headache medicine such as sumatriptan (Imitrex) or zolmitriptan (Zomig); or

narcotic medication such as levomethadyl (Orlaam), or methadone (Dolophine, Methadose).

This list is not complete and there may be other drugs that can interact with Saphris. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Geodon

Geodon

Generic Name: ziprasidone (zi PRAY si done)

What is Geodon?

Geodon (ziprasidone) is an antipsychotic medication. It works by changing the effects of chemicals in the brain.

Geodon is used to treat schizophrenia and the manic symptoms of bipolar disorder (manic depression) in adults and children who are at least 10 years old.

Geodon may also be used for other purposes not listed in this medication guide.

Important information about Geodon

Geodon is not for use in psychotic conditions related to dementia. Geodon may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

Do not use Geodon if you have a personal or family history of “Long QT syndrome,” if you have recently had a heart attack, or if you have uncontrolled heart failure.

Stop taking Geodon and call your doctor right away if you feel dizzy or light-headed, have a fast or pounding heartbeat, or if you faint. This could be signs of a serious heart rhythm problem.

There are many other medicines that can cause serious or life-threatening medical problems if you take them together with Geodon. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Before taking Geodon

Geodon is not for use in psychotic conditions related to dementia. Geodon may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions. Do not use this medication if you are allergic to ziprasidone, or if you have:

a personal or family history of “Long QT syndrome”;

history of recent heart attack; or

uncontrolled or untreated heart failure.

Geodon should never be taken together with any of the following drugs, or a life-threatening heart rhythm disorder could occur:

arsenic trioxide (Trisenox);

dolasetron (Anzemet);

droperidol (Inapsine);

halofantrine (Halfan);

mefloquine (Lariam);

levomethadyl acetate (no longer available in the U.S.);

tacrolimus (Prograf);

antibiotics such as gatifloxacin (Tequin), pentamidine (NebuPent, Pentam), moxifloxacin (Avelox), sparfloxacin (Zagam), telithromycin (Ketek);

heart rhythm medicine such as dofetilide (Tikosyn), disopyramide (Norpace), quinidine (Cardioquin, Quinaglute), or sotalol (Betapace); or

medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), mesoridazine (Serentil), pimozide (Orap), or thioridazine (Mellaril).

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take Geodon:

a heart rhythm disorder;

a history of heart attack or stroke;

a history of bone marrow or blood cell disorder;

low blood levels of potassium or magnesium;

diabetes (Geodon may raise your blood sugar);

seizures or epilepsy;

a history of suicidal thoughts;

Parkinson’s disease, Alzheimer’s;

trouble swallowing;

kidney disease.

Geodon may cause you to have high blood sugar (hyperglycemia). Talk to your doctor if you have any signs of hyperglycemia such as increased thirst or urination, excessive hunger, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking Geodon.

The orally disintegrating tablet may contain phenylalanine. Talk to your doctor before using this form of Geodon if you have phenylketonuria (PKU).

FDA pregnancy category C. It is not known whether Geodon is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether ziprasidone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from Geodon.

How should I take Geodon?

Take Geodon exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

To be sure Geodon is not causing harmful effects, your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled appointments.

Take this medicine with food.

It is important to take Geodon regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

It may take several weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve. Store Geodon at room temperature away from moisture, light, and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical treatment if you think you have used too much of this medicine. Overdose symptoms may include drowsiness, problems with speech, dizziness, feeling light-headed, fainting, fast or pounding heartbeat, or restless muscle movements in your eyes, tongue, jaw, or neck.

What should I avoid while taking Geodon?

While you are taking Geodon, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking this medicine. Geodon can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of Geodon.

Geodon side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Geodon and call your doctor at once if you have any of these serious side effects:

dizziness, feeling light-headed, fainting, fast or pounding heartbeat;

stiff muscles, confusion, sweating, fast or uneven heartbeats;

fever, chills, body aches, flu symptoms;

white patches or sores inside your mouth or on your lips;

tremor (uncontrolled shaking), restless muscle movements in your eyes, tongue, jaw, or neck;

agitation, hostility, confusion;

increased thirst or urination, weakness, extreme hunger; or

penis erection that is painful or lasts 4 hours or longer.

Less serious Geodon side effects may include:

mild skin rash;

anxiety, headache, depressed mood;

dizziness, drowsiness;

muscle pain or twitching;

nausea, vomiting, loss of appetite;

runny or stuffy nose, cough, sore throat; or

weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Geodon?

Before taking Geodon, tell your doctor if you regularly use any other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Geodon.

Tell your doctor about all other medications you are using, especially:

a diuretic (water pill), blood pressure medicine, or heart rhythm medicine;

carbamazepine (Carbatrol, Tegretol);

cisapride (Propulsid);

haloperidol (Haldol);

narcotic pain medication;

medicines used to treat Parkinson’s Disease such as levodopa (Dopar, Larodopa, Sinemet, Atamet, others); or

antibiotics such as azithromycin (Zithromax), clarithromycin (Biaxin), erythromycin (E-Mycin, E.E.S., Erythrocin, Ery-Tab), ketoconazole (Nizoral), or telithromycin (Ketek).

This list is not complete and there may be other drugs that can interact with Geodon. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Risperdal

Risperdal

Generic Name: risperidone (oral) (ris PER i done)

What is Risperdal?

Risperdal is an antipsychotic medication. It is an “atypical antipsychotic”. It works by changing the effects of chemicals in the brain.

Risperdal is used to treat schizophrenia and symptoms of bipolar disorder (manic depression). It is also used in autistic children to treat symptoms of irritability.

Risperdal may also be used for purposes other than those listed in this medication guide.

Important information about Risperdal

Risperdal is not for use in psychotic conditions related to dementia. Risperidone may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

Do not give Risperdal to a child without a doctor’s advice.

While you are taking Risperdal, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking this medication. Risperdal can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of Risperdal. Stop using this medication and call your doctor at once if you have fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, restless muscle movements in your face or neck, tremor (uncontrolled shaking), trouble swallowing, feeling light-headed, or fainting.

There may be other drugs not listed that can affect this medication. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Before taking Risperdal

Risperdal is not for use in psychotic conditions that are related to dementia. Risperdal has caused fatal heart attack and stroke in older adults with dementia-related conditions. You should not use this medication if you are allergic to risperidone.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take Risperdal:

kidney disease;

heart disease, high blood pressure, heart rhythm problems;

a history of heart attack or stroke;

a history of low white blood cell (WBC) counts;

a history of breast cancer;

seizures or epilepsy;

diabetes (risperidone may raise your blood sugar);

a history of suicidal thoughts;

Parkinson’s disease; or

trouble swallowing.

Risperdal may cause you to have high blood sugar (hyperglycemia). Talk to your doctor if you have any signs of hyperglycemia such as increased thirst or urination, excessive hunger, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking Risperdal.

The risperidone orally disintegrating tablet may contain phenylalanine. Talk to your doctor before using this form of risperidone if you have phenylketonuria (PKU).

FDA pregnancy category C. It is not known whether Risperdal is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether risperidone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give Risperdal to a child without a doctor’s advice.

How should I take Risperdal?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Risperdal can be taken with or without food.

To take risperidone orally disintegrating tablets (Risperdal M-Tabs):

Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.

Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away.

Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

Swallow several times as the tablet dissolves. If desired, you may drink liquid after the tablet is completely dissolved.

It is important to take Risperdal regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Measure the liquid form of Risperdal with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not mix the liquid form of Risperdal with cola or tea. It may take several weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve. Store Risperdal at room temperature away from moisture, light, and heat. Do not allow the liquid form of Risperdal to freeze.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical treatment if you think you have used too much of this medicine.

Overdose symptoms may include drowsiness, fast heart rate, feeling light-headed, fainting, and restless muscle movements in your eyes, tongue, jaw, or neck.

What should I avoid while taking Risperdal?

While you are taking Risperdal, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking risperidone.

Risperdal can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of Risperdal.

Risperdal side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Risperdal and call your doctor at once if you have any of these serious side effects:

fever, stiff muscles, confusion, sweating, fast or uneven heartbeats;

restless muscle movements in your eyes, tongue, jaw, or neck;

tremor (uncontrolled shaking);

fever, chills, body aches, flu symptoms;

white patches or sores inside your mouth or on your lips;

trouble swallowing; or

feeling light-headed, fainting.

Less serious Risperdal side effects may include:

mild restlessness, drowsiness, or tremor;

sleepiness, dreaming more than usual;

blurred vision;

dizziness or headache;

weight gain;

problems with urination;

nausea, dry mouth, constipation; or

decreased sex drive, impotence, or difficulty having an orgasm.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Risperdal?

Before you take Risperdal, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Risperdal.

Also tell your doctor if you are taking any of the following medicines:

carbamazepine (Carbatrol, Tegretol);

phenytoin (Dilantin);

phenobarbital (Luminal, Solfoton);

clozapine (Clozaril);

fluoxetine (Prozac) or paroxetine (Paxil);

rifampin (Rifadin, Rimactane, Rifater); or

medicines used to treat Parkinson’s Disease such as levodopa (Dopar, Larodopa, Sinemet, Atamet, others), bromocriptine (Parlodel, others), pergolide (Permax), pramipexole (Mirapex), or ropinirole (Requip).

This list is not complete and there may be other drugs that can interact with Risperdal. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Clozaril

Clozaril

Generic Name: clozapine (KLOE za peen)

What is Clozaril?

Clozaril is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

Clozaril is used to treat severe schizophrenia symptoms in people who have not responded to other medications. It is also used to help reduce the risk of suicidal behavior in people with schizophrenia or similar disorders.

Clozaril may also be used for other purposes not listed in this medication guide.

Important information about Clozaril

Clozaril is not for use in psychotic conditions related to dementia. Clozaril may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

You should not take Clozaril if you have uncontrolled epilepsy, paralytic ileus or intestinal blockage, an infection caused by Clozaril, or if you are also using drugs that weaken your immune system (such as cancer medicine or steroids).

While you are taking Clozaril, your blood may need to be tested every week for the first 6 months of treatment. Do not miss any scheduled blood tests.

Do not stop taking Clozaril or change your dose without first talking to your doctor.

Call your doctor if you have shortness of breath, swelling in your hands or feet, fever, weakness, sore throat, sudden numbness or weakness, sudden vision or speech problems, chest pain, cough, wheezing, pain or swelling in one or both legs, mouth sores, seizure, or jaundice (yellowing of your skin or eyes).

There are many other medicines that can interact with Clozaril. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Before taking Clozaril

Clozaril is not for use in psychotic conditions related to dementia. Clozaril may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions. You should not take Clozaril if you are allergic to clozapine, or if you have:

untreated or uncontrolled epilepsy;

paralytic ileus or intestinal blockage;

a history of infection while taking Clozaril; or

if you are also using drugs that weaken your immune system (such as cancer medicine or steroids).

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before taking Clozaril, tell your doctor if you have:

heart disease, heart rhythm disorder, high blood pressure, or a history of heart attack;

lung disease;

diabetes;

a history of bone marrow or blood cell disorders;

glaucoma; or

an enlarged prostate or urination problems.

Clozaril may raise your blood sugar, causing symptoms such as increased thirst, loss of appetite, increased urination, drowsiness, nausea, or fruity breath odor. Call your doctor right away if you have any of these symptoms.

FDA pregnancy category B: This medication is not expected to be harmful to an unborn baby. Do not use Clozaril without telling your doctor if you are pregnant or plan to become pregnant during treatment. Clozaril can pass into breast milk and may harm a nursing baby. You should not use this medication if you are breast-feeding a baby.

How should I take Clozaril?

Take Clozaril exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor. Follow the directions on your prescription label.

Clozaril can be taken with or without food.

Take the regular oral tablet (Clozaril) with a full glass of water.

The orally-disintegrating tablet (FazaClo) can be taken without water. Gently peel back the foil from the blister pack and drop the tablet onto your dry hand. Do not push tablet through the foil. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet.

If your doctor has prescribed one-half of an orally-disintegrating tablet, you will need to break the tablet in half. Throw the other half away. Do not store it for later use.

While you are taking Clozaril, your blood may need to be tested every week for the first 6 months of treatment. Do not miss any scheduled blood tests. After 6 months, blood tests may be needed less often.

If you stop taking Clozaril for more than 2 days in a row, call your doctor before you start taking it again. You may need a lower dose. Do not stop taking Clozaril or change your dose without first talking to your doctor. If you need to have any type of surgery, tell the surgeon ahead of time that you are using Clozaril. Store this medicine at room temperature away from moisture and heat. Keep each FazaClo tablet in the unopened blister pack until you are ready to take the medicine.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include confusion, fast heart rate, drowsiness, drooling, weak or shallow breathing, feeling like you might pass out, and seizure (convulsions).

What should I avoid while taking Clozaril?

Clozaril may cause seizures, dizziness, or fainting. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of Clozaril.

Clozaril side effects

Stop using Clozaril and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

feeling short of breath, even at night or with mild exertion;

swelling in your hands or feet;

fever, weakness, sore throat, stiff muscles, confusion, sweating, fast or uneven heartbeats;

sudden numbness or weakness, especially on one side of the body;

sudden headache, confusion, problems with vision, speech, or balance;

chest pain, sudden cough, wheezing, rapid breathing, fast heart rate, pain or swelling in one or both legs;

white patches or sores inside your mouth or on your lips;

nausea, vomiting, loss of appetite, and jaundice (yellowing of your skin or eyes); or

seizure (black-out or convulsions).

Less serious side effects may include:

constipation;

drooling, especially at night;

increased sweating;

drowsiness, dizziness, spinning sensation;

sleep problems or nightmares; or

weight gain.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Clozaril?

Before taking Clozaril, tell your doctor if you are using any of the following drugs:

cimetidine (Tagamet);

citalopram (Celexa);

lithium (Eskalith, Lithobid);

rifampin (Rifadin, Rimactane);

blood pressure medications;

heart rhythm medications such as propafenone (Rythmol) or flecaininde (Tambocor);

seizure medicine such as phenytoin (Dilantin) or carbamazepine (Carbatrol, Tegretol);

antibiotics such as ciprofloxacin (Cipro) or erythromycin (E-Mycin, E.E.S, Ery-Tab);

atropine (Donnatal, and others), belladonna, clidinium (Quarzan), dicyclomine (Bentyl), scopolamine (Transderm-Scop); or

diazepam (Valium) or similar medicines such as alprazolam (Xanax), clonazepam (Klonopin), lorazepam (Ativan), midazolam (Versed), temazepam (Restoril), and others.

This list is not complete and there may be other drugs that can interact with Clozaril. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Abilify

Abilify

Generic Name: aripiprazole (AR i PIP ra zole)

What is Abilify?

Abilify (aripiprazole) is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

Abilify is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression). It is also used together with other medications to treat major depressive disorder in adults.

Abilify may also be used for other purposes not listed in this medication guide.

Important information about Abilify

Abilify is not for use in psychotic conditions that are related to dementia. Abilify may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions. Stop using Abilify and call your doctor at once if you have the following symptoms: fever with stiff muscles and rapid heart rate; uncontrolled muscle movements; symptoms that come on suddenly such as numbness or weakness, severe headache, and problems with vision, speech, or balance. Abilify can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which can increase some of the side effects of Abilify.

Before you take aripiprazole, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Abilify.

Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking Abilify.

What should I discuss with my healthcare provider before taking Abilify?

Abilify is not for use in psychotic conditions that are related to dementia. Abilify may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

You should not use this medicine if you are allergic to aripiprazole. If you have any of these other conditions, you may need a dose adjustment or special tests to safely take Abilify:

heart disease, high blood pressure, heart rhythm problems;

a history of heart attack or stroke;

a history of low white blood cell (WBC) counts;

a history of breast cancer;

seizures or epilepsy;

a personal or family history of diabetes; or

trouble swallowing.

The liquid form (oral solution) of this medication may contain up to 15 grams of sugar per dose. Before taking Abilify oral solution, tell your doctor if you have diabetes. The orally disintegrating tablet form of this medication may contain over 3 milligrams of phenylalanine per tablet. Before taking Abilify Discmelt, tell your doctor if you have phenylketonuria.

Abilify may cause you to have high blood sugar (hyperglycemia). Talk to your doctor if you have any signs of hyperglycemia such as increased thirst or urination, excessive hunger, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking Abilify.

FDA pregnancy category C. It is not known whether Abilify is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Abilify can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Abilify?

Take Abilify exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Do not take aripiprazole for longer than 6 weeks unless your doctor has told you to. Take each dose with a full glass of water.

Abilify can be taken with or without food.

Abilify is usually taken once a day. Follow your doctor ’s instructions.

Measure the liquid form of Abilify with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

To take aripiprazole orally disintegrating tablets (Abilify Discmelt):

Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.

Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away.

Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet.

It is important to take Abilify regularly to get the most benefit.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. It is important that you not miss any scheduled visits to your doctor.

Store Abilify tablets at room temperature away from moisture and heat.

Abilify oral solution should be stored in the refrigerator and can be used for up to 6 months after opening.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include drowsiness, vomiting, agitation, aggression, confusion, tremors, fast or slow heart rate, seizure (convulsions), trouble breathing, feeling light-headed, or fainting.

What should I avoid while taking Abilify?

Abilify can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid drinking alcohol, which can increase some of the side effects of Abilify.

Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking Abilify.

Abilify side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Abilify and call your doctor at once if you have any of these serious side effects:

fever, stiff muscles, confusion, sweating, fast or uneven heartbeats;

jerky muscle movements you cannot control;

sudden numbness or weakness, headache, confusion, or problems with vision, speech, or balance;

fever, chills, body aches, flu symptoms;

white patches or sores inside your mouth or on your lips;

increased thirst or urination, loss of appetite, fruity breath odor, drowsiness, dry skin, nausea, and vomiting;

seizure (convulsions);

thoughts of hurting yourself;

feeling like you might pass out;

jaundice (yellowing of your skin or eyes); or

urinating less than usual or not at all.

Less serious Abilify side effects may include:

choking or trouble swallowing;

dizziness, drowsiness, or weakness;

constipation, mild stomach upset;

headache, anxiety;

sleep problems (insomnia); or

weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Abilify?

Before you take Abilify, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Abilify.

Also tell your doctor if you are taking any of the following medicines:

Before taking Abilify, tell your doctor if you are taking any of the following medicines:

a medication to treat high blood pressure or a heart condition;

carbamazepine (Tegretol), phenobarbital (Luminal, Solfoton), or phenytoin (Dilantin);

rifabutin (Mycobutin) or rifampin (Rifadin, Rimactane, Rifater);

ketoconazole (Nizoral), itraconazole (Sporanox);

quinidine (Cardioquin, Quinaglute); or

fluoxetine (Prozac), fluvoxamine (Luvox), or paroxetine (Paxil).

This list is not complete and there may be other drugs that can interact with Abilify. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Invega

Invega

Generic Name: paliperidone (pal ee PER i done)

What is Invega?

Invega (paliperidone) is an atypical antipsychotic medication. Exactly how it works is not known. It is thought to work by changing certain substances in the brain.

Invega is used for the acute and maintenance treatment of schizophrenia.

Invega may also be used for other purposes not listed in this medication guide.

Important information about Invega

Invega is not for use in psychotic conditions related to dementia. Invega may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

While you are taking Invega, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking paliperidone.

Invega can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Before using Invega, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Invega.

Avoid drinking alcohol. It can increase some of the side effects of Invega. Stop using paliperidone and call your doctor at once if you have fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, restless muscle movements in your face or neck, tremor (uncontrolled shaking), trouble swallowing, feeling light-headed, or fainting.

Before taking Invega

Invega is not for use in psychotic conditions related to dementia. Invega may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions. You should not use Invega if you are allergic to paliperidone or a similar drug called risperidone (Risperdal).

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take Invega, tell your doctor if you have:

a history of low white blood cell (WBC) counts;

a personal or family history of Long QT syndrome;

heart disease, heart rhythm problems, or a history of heart attack or stroke;

high or low blood pressure;

an electrolyte imbalance, such as low potassium or magnesium levels in your blood;

a history of breast cancer;

seizures or epilepsy;

kidney or liver disease;

diabetes (Invega may raise your blood sugar);

a stomach or intestinal disorder;

a history of suicidal thoughts;

Parkinson’s disease; or

trouble swallowing.

FDA pregnancy category C. It is not known whether Invega is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Paliperidone passes into breast milk and could cause harm to a nursing baby. Do not use Invega without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from this medicine.

How should I take Invega?

Take Invega exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Invega can be taken with or without food.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

It is important to take Invega regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments.

Invega may cause you to have high blood sugar (hyperglycemia). Talk to your doctor if you have any signs of hyperglycemia such as increased thirst or urination, excessive hunger, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking Invega.

Store Invega at room temperature away from moisture, light, and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical treatment if you think you have used too much of this medicine.

Overdose symptoms may include drowsiness, fast heart rate, feeling light-headed, fainting, and restless muscle movements in your eyes, tongue, jaw, or neck.

What should I avoid while taking Invega?

While you are taking Invega, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking paliperidone. Invega can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of Invega.

Invega side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Invega and call your doctor at once if you have any of these serious side effects:

very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, feeling like you might pass out;

restless muscle movements in your eyes, tongue, jaw, or neck;

tremor (uncontrolled shaking);

trouble swallowing;

sudden numbness or weakness, especially on one side of the body;

sudden and severe headache, or problems with vision, speech, or balance;

fever, chills, body aches, flu symptoms; or

white patches or sores inside your mouth or on your lips.

Less serious Invega side effects may include:

breast swelling or discharge;

changes in menstrual periods;

mild restlessness, drowsiness, or tremor;

blurred vision;

dizziness or headache;

weight gain;

nausea, dry mouth, upset stomach; or

decreased sex drive, impotence, or difficulty having an orgasm.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Invega?

Before using Invega, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Invega.

The following drugs can interact with Invega. Tell your doctor if you are using any of these:

arsenic trioxide (Trisenox);

blood pressure medications;

carbamazepine (Carbatrol, Tegretol);

droperidol (Inapsine);

an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), levofloxacin (Levaquin), moxifloxacin (Avelox), or pentamidine (NebuPent, Pentam);

an antidepressant such as amitriptylline (Elavil, Vanatrip), clomipramine (Anafranil), or desipramine (Norpramin);

anti-malaria medications such as chloroquine (Arelan) or mefloquine (Lariam);

heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), ibutilide (Corvert), procainamide (Procan, Pronestyl), propafenone (Rythmol), quinidine (Quinidex, Quin-Release Quin-G), or sotalol (Betapace);

medicine to prevent or treat nausea and vomiting, such as dolasetron (Anzemet) or ondansetron (Zofran);

medicines to treat Parkinson’s Disease such as levodopa (Dopar, Larodopa, Sinemet, Atamet, others), bromocriptine (Parlodel, others), pramipexole (Mirapex), or ropinirole (Requip);

medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon);

migraine headache medicine such as sumatriptan (Imitrex) or zolmitriptan (Zomig); or

narcotic medication such as levomethadyl (Orlaam), or methadone (Dolophine, Methadose).

This list is not complete and there may be other drugs that can affect Invega. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Zyprexa

Zyprexa

Generic Name: olanzapine (oh LANZ a peen)

What is Zyprexa?

Zyprexa (olanzapine) is an atypical antipsychotic medication. Exactly how it works is not known. It is thought to work by changing the actions of certain chemicals in the brain.

Zyprexa is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression) in adults and children who are at least 10 years old.

Zyprexa is sometimes used together with another medication called fluoxetine (Prozac, Sarafem). This combination is also used to treat depression after at least two other medications have been tried without successful treatment of symptoms.

Zyprexa may also be used for other purposes not listed in this medication guide.

Important information about Zyprexa

Zyprexa is not for use in psychotic conditions related to dementia. Olanzapine may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

Zyprexa may cause you to have high blood sugar (hyperglycemia). Symptoms include increased thirst, loss of appetite, increased urination, nausea, vomiting, drowsiness, dry skin, and dry mouth. If you are diabetic, check your blood sugar levels on a regular basis while you are taking Zyprexa.

It may take up to 4 weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 4 weeks of treatment. Zyprexa can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid drinking alcohol, which can increase some of the side effects of Zyprexa. Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking Zyprexa.

Before taking Zyprexa

Zyprexa is not for use in psychotic conditions related to dementia. Zyprexa may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Zyprexa:

liver disease;

kidney disease;

heart disease, high blood pressure, heart rhythm problems;

a history of low white blood cell (WBC) counts;

high cholesterol or triglycerides;

a history of heart attack or stroke;

a history of breast cancer;

seizures or epilepsy;

a personal or family history of diabetes;

an enlarged prostate or difficulty urinating;

glaucoma; or

trouble swallowing.

FDA pregnancy category C. It is not known whether Zyprexa is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. Olanzapine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

The olanzapine orally disintegrating tablet (Zyprexa Zydis) may contain phenylalanine. Talk to your doctor before using this form of olanzapine if you have phenylketonuria (PKU).

How should I take Zyprexa?

Take Zyprexa exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Zyprexa can be taken with or without food.

This medicine is usually taken once a day. Follow your doctor’s instructions.

To take olanzapine orally disintegrating tablets (Zyprexa Zydis):

Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.

Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away.

Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet.

It may take up to 4 weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 4 weeks of treatment.

Zyprexa may cause you to have high blood sugar (hyperglycemia). Symptoms include increased thirst, loss of appetite, increased urination, nausea, vomiting, drowsiness, dry skin, and dry mouth. If you are diabetic, check your blood sugar levels on a regular basis while you are taking Zyprexa.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments.

Store Zyprexa at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include drowsiness, agitation, aggression, slurred speech, confusion, increased heart rate, jerky or uncontrolled muscle movements, trouble breathing, or fainting.

What should I avoid while taking Zyprexa?

Zyprexa can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid drinking alcohol, which can increase some of the side effects of Zyprexa. Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking this medicine.

Zyprexa side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Zyprexa: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Zyprexa and call your doctor at once if you have any of these serious side effects:

fever, stiff muscles, sweating, fast or uneven heartbeats;

jerky muscle movements you cannot control;

sudden numbness or weakness, especially on one side of the body;

sudden headache, confusion, problems with vision, speech, or balance;

fever, chills, body aches, flu symptoms;

white patches or sores inside your mouth or on your lips;

increased thirst, frequent urination, excessive hunger, or weakness;

feeling light-headed, fainting;

unusual thoughts or behavior, hallucinations, or thoughts about hurting yourself; or

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious Zyprexa side effects may include:

dizziness, drowsiness, or weakness;

constipation;

dry mouth;

swelling in your hands or feet;

back pain;

weight gain, increased appetite; or

upset stomach.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Zyprexa?

Before using Zyprexa, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Zyprexa.

The following drugs can interact with Zyprexa. Tell your doctor if you are using any of these:

a medication to treat high blood pressure or a heart condition;

carbamazepine (Tegretol);

fluvoxamine (Luvox); or

a medication to treat Parkinson’s disease including levodopa (Sinemet, Larodopa, Atamet), selegiline (Eldepryl, Emsam), pramipexole (Mirapex), ropinirole (Requip), and others.

This list is not complete and there may be other drugs that can interact with Zyprexa. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Seroquel

Seroquel

Generic Name: quetiapine (kwe TYE a peen)

What is Seroquel?

Seroquel is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

Seroquel is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression) in adults and children who are at least 10 years old.

Seroquel may also be used for purposes other than those listed in this medication guide.

Important information about Seroquel

Seroquel is not for use in psychotic conditions related to dementia. Seroquel may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions. Stop using Seroquel and call your doctor at once if you have the following symptoms: fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, uncontrolled muscle movements, symptoms that come on suddenly such as numbness or weakness, severe headache, and problems with vision, speech, or balance.

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Before taking Seroquel

Seroquel is not for use in psychotic conditions that are related to dementia. Seroquel may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take Seroquel:

heart disease, high blood pressure, heart rhythm problems;

a history of heart attack or stroke;

a history of low white blood cell (WBC) counts;

a thyroid disorder;

seizures or epilepsy;

high cholesterol or triglycerides;

a personal or family history of diabetes; or

trouble swallowing.

Seroquel may cause you to have high blood sugar (hyperglycemia). Talk to your doctor if you have any signs of hyperglycemia such as increased thirst or urination, excessive hunger, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking Seroquel.

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Tell your doctor if you have worsening symptoms of depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

FDA pregnancy category C. It is not known whether Seroquel is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether quetiapine passes into breast milk or if it could harm a nursing baby. Do not use Seroquel without telling your doctor if you are breast-feeding a baby. Do not give Seroquel to anyone younger than 18 years old without the advice of a doctor.

How should I take Seroquel?

Take Seroquel exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the instructions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from Seroquel.

Take each dose with a full glass of water. Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. Breaking the pill may cause too much of the drug to be released at one time.

To be sure Seroquel is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments.

Store Seroquel tablets at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include extreme drowsiness, fast heart rate, feeling light-headed, or fainting.

What should I avoid while taking Seroquel?

Seroquel can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid drinking alcohol, which can increase some of the side effects of Seroquel.

Seroquel side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Seroquel: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Other serious side effects include:

fever, stiff muscles, confusion, sweating, fast or uneven heartbeats;

jerky muscle movements you cannot control;

sudden numbness or weakness, especially on one side of the body;

sudden headache, confusion, problems with vision, speech, or balance;

fever, chills, body aches, flu symptoms;

white patches or sores inside your mouth or on your lips;

increased thirst, frequent urination, excessive hunger, or weakness;

feeling like you might pass out; or

urinating less than usual or not at all.

Less serious Seroquel side effects may include:

dizziness, drowsiness, or weakness;

dry mouth, runny nose, sore throat;

nausea, vomiting, stomach pain, constipation;

blurred vision, headache, anxiety, agitation;

breast swelling or discharge;

missed menstrual periods; or

weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Seroquel?

Before taking Seroquel, tell your doctor if you are taking any of the following medicines:

cimetidine (Tagamet);

erythromycin (E-Mycin, E.E.S, Ery-Tab);

lorazepam (Ativan);

rifabutin (Mycobutin) or rifampin (Rifadin, Rimactane, Rifater);

steroids (prednisone and others);

thioridazine (Mellaril);

an antifungal medication such as erythromycin (E-Mycin, E.E.S, Ery-Tab), fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox);

medicine for depression or mental illness, such as fluoxetine (Prozac), haloperidol (Haldol), imipramine (Tofranil), or risperidone (Risperdal);

a medication to treat high blood pressure or a heart condition; or

seizure medication such as carbamazepine (Tegretol), divalproex (Depakote), phenobarbital (Luminal, Solfoton), phenytoin (Dilantin), or valproate (Depakene).

This list is not complete and there may be other drugs that can interact with Seroquel. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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