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Archive for the ‘cholinergic muscle stimulants’ Category

Tensilon

Posted by admin on November 5th, 2009

Tensilon

Generic Name: edrophonium (ED roe FOE nee um)

What is Tensilon (edrophonium)?

Edrophonium is used as part of a medical test to help diagnose a muscle disorder called myasthenia gravis.

Edrophonium is sometimes used to reverse the effects of certain medications used to prevent muscle contractions during surgical procedures.

Edrophonium may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Tensilon (edrophonium)?

You should not receive this medication if you are allergic to edrophonium, or have a blockage in your intestines or obstructed urine flow.

Before you receive edrophonium, tell your doctor if you have asthma, a heart rhythm disorder, or if you are allergic to sulfites. Also tell your doctor if you are pregnant or breast-feeding.

Tell your caregivers at once if you have a serious side effect such as slow heart rate, chest pain, weak pulse, fainting, weak or shallow breathing, increased urination, seizures, or trouble swallowing.

Less serious side effects may occur (some of which can be expected as part of a positive test reaction to edrophonium) such as watery eyes, vision problems, changes in your voice, mild nausea, vomiting, stomach pain, weakness, or muscle twitching.

What should I discuss with my health care provider before receiving Tensilon (edrophonium)?

You should not receive this medication if you are allergic to edrophonium, or have certain conditions. Be sure your doctor knows if you have:

a blockage in your intestines; or

obstructed urine flow.

Before you receive edrophonium, tell your doctor if you are allergic to any drugs, or if you have:

asthma;

a heart rhythm disorder; or

if you are allergic to sulfites.

If you have any of these conditions, you may need a dose adjustment or special tests to safely receive edrophonium.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant before you receive edrophonium. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is edrophonium given?

Edrophonium is given as an injection through a needle placed into a muscle or vein. You will receive this injection in a clinic or hospital setting as part of a medical test.

When used in diagnosing myasthenia gravis, edrophonium is given in small doses over 15 to 45 seconds. After each dose you will be observed for the expected reaction to this medication (muscle twitching, vision changes, increased muscle weakness, sweating, stomach cramps, nausea, and other symptoms). You may receive other medications to treat the reaction to edrophonium.

The test you are receiving may be repeated a second time.

Your specific edrophonium test may be performed in a different manner than described above.

What happens if I miss a dose?

Since edrophonium is given by a healthcare professional, it is not likely that you will miss a dose.

What happens if I overdose?

Tell your caregivers right away if you think you have received too much of this medicine.

Overdose symptoms may include nausea, vomiting, diarrhea, sweating, slow heart rate, and increased salivation (drooling).

What should I avoid after receiving Tensilon (edrophonium)?

Follow your doctor’s instructions about any restrictions on food, beverages, or activity after you have been treated with edrophonium.

Tensilon (edrophonium) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Tell your caregivers at once if you have a serious side effect such as:

slow heart rate;

chest pain, weak pulse, increased sweating, and dizziness;

feeling like you might pass out;

weak or shallow breathing;

urinating more than usual;

seizures (convulsions); or

trouble swallowing.

Less serious side effects (some of which can be expected as part of a positive test reaction) may include:

watery eyes, vision problems;

changes in your voice;

mild nausea, vomiting, diarrhea, stomach pain;

weakness; or

muscle twitching.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Tensilon (edrophonium)?

There may be other drugs that can interact with edrophonium. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

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Regonol

Posted by admin on November 5th, 2009

Regonol

Regonol is used for:

Treating myasthenia gravis. It may also be used for other conditions as determined by your doctor.

Regonol is a cholinesterase inhibitor. It works by improving nerve impulses in muscles so that the muscles are better able to work.

Do NOT use Regonol if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Regonol :

Some medical conditions may interact with Regonol . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Regonol . Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Regonol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Regonol :

Use Regonol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Regonol .

Important safety information:

Possible side effects of Regonol :

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); diarrhea; fainting; increased production of saliva; increased sweating; muscle weakness; nausea; small pupils; stomach cramps; trouble breathing; vision changes; vomiting; weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Regonol is usually handled and stored by a health care provider. If you are using Regonol at home, store Regonol as directed by your pharmacist or health care provider. Keep Regonol out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Regonol . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Regonol resources

Compare Regonol with other medications for the treatment of:

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Prostigmin Bromide

Posted by admin on November 5th, 2009

Prostigmin Bromide

Generic Name: neostigmine (nee o STIG meen)

What is Prostigmin Bromide (neostigmine)?

Neostigmine affects chemicals in the body that are involved in the communciation between nerve impulses and muscle movement.

Neostigmine is used to treat the symptoms of myasthenia gravis.

Neostigmine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Prostigmin Bromide (neostigmine)?

Do not use neostigmine if you have a serious stomach condition called peritonitis, or if you have a bladder or bowel obstruction.

Before using neostigmine, tell your doctor if you have asthma, epilepsy or other seizure disorder, a heart rhythm disorder, circulation or blood vessel problems, an overactive thyroid, or a stomach ulcer.

The amount and timing of this medicine is extremely important to the success of your treatment. Carefully follow your doctor’s instructions about how much medicine to take and when to take it.

Your doctor may occasionally change your dose to make sure you get the best results from this medication. You may be asked to keep a daily record of when you took each dose and how long the effects lasted. This will help your doctor determine if your dose needs to be adjusted.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking neostigmine. You may need to stop using the medicine for a short time.

What should I discuss with my health care provider before taking Prostigmin Bromide (neostigmine)?

Do not use neostigmine if you have:

a serious stomach condition called peritonitis; or

a bladder or bowel obstruction.

Before using neostigmine, tell your doctor if you have:

asthma;

epilepsy or other seizure disorder;

a heart rhythm disorder;

problems with your blood vessels or circulation;

overactive thyroid; or

a stomach ulcer.

If you have any of these conditions, you may not be able to use neostigmine, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether neostigmine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Prostigmin Bromide (neostigmine)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

The amount and timing of this medicine is extremely important to the success of your treatment. Carefully follow your doctor’s instructions about how much medicine to take and when to take it.

Your doctor may occasionally change your dose to make sure you get the best results from this medication. You may be asked to keep a daily record of when you took each dose and how long the effects lasted. This will help your doctor determine if your dose needs to be adjusted.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking neostigmine. You may need to stop using the medicine for a short time.

Store neostigmine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Symptoms of a neostigmine overdose may include extreme muscle weakness, confusion, seizure (convulsions), severe diarrhea, muscle twitching, wheezing, chest tightness, and problems with vision or speech.

What should I avoid while taking Prostigmin Bromide (neostigmine)?

There are no restrictions on food, beverages, or activity while using neostigmine unless your doctor has told you otherwise.

Prostigmin Bromide (neostigmine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

severe diarrhea;

seizure (convulsions);

feeling light-headed, fainting;

vision problems; or

fast, slow, or uneven heartbeats.

Other less serious side effects are more likely to occur, such as:

sweating or urinating more than usual;

drooling, watery eyes;

warmth or tingly feeling;

nausea, vomiting, mild stomach pain;

dizziness, drowsiness, weakness, headache;

mild itching or skin rash; or

muscle cramps, joint pain.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Prostigmin Bromide (neostigmine)?

Before taking neostigmine, tell your doctor if you are using any of the following drugs:

atropine (Donnatal, and others);

belladonna;

clidinium (Quarzan);

dicyclomine (Bentyl);

glycopyrrolate (Robinul);

hyoscyamine (Anaspaz, Cystospaz, Levsin);

mepenzolate (Cantil);

methantheline (Provocholine);

methscopolamine (Pamine);

propantheline (Pro-Banthine);

scopolamine (Transderm-Scop);

antibiotics such as neomycin (Mycafradin, Neo-Tab), kanamycin (Kantrex), or streptomycin; or

heart rhythm medications such as quinidine (Quinidex, Quinaglute), procainamide (Procan, Pronestyl), disopyramide (Norpace), mexiletine (Mexitil), tocainide (Tonocard), flecainide (Tambocor), propafenone (Rythmol), esmolol (Brevibloc), propranolol (Inderal), metoprolol (Toprol), amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), sotalol (Betapace).

If you are using any of these drugs, you may not be able to use neostigmine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect neostigmine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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Prostigmin

Posted by admin on November 5th, 2009

Prostigmin

Prostigmin is used for:

Treating myasthenia gravis. It may also be used for other conditions as determined by your doctor.

Prostigmin is a cholinesterase inhibitor. It works by improving the transmission of nerve impulses in muscles so that the muscles are better able to work.

Do NOT use Prostigmin if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Prostigmin :

Some medical conditions may interact with Prostigmin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Prostigmin . Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Prostigmin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Prostigmin :

Use Prostigmin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Prostigmin .

Important safety information:

Possible side effects of Prostigmin :

All medicines may cause side effects, but many people have no, or minor, side effects.

Abdominal cramps; diarrhea; difficulty speaking; dilation of pupils; dizziness; drowsiness; excess saliva; frequent urination; gas; headache; increased sweating; joint pain; muscle twitching; weakness.

Severe allergic reactions (rash; itching; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fainting; increased muscle weakness; interrupted breathing; irregular heartbeat; seizures; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Store Prostigmin at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Prostigmin out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Prostigmin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Prostigmin resources

Compare Prostigmin with other medications for the treatment of:

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Mytelase Chloride

Posted by admin on November 5th, 2009

Mytelase Chloride

Generic Name: ambenonium (am ben OH nee um)

What is Mytelase Chloride (ambenonium)?

Ambenonium affects chemicals in the body that are involved in the communication between nerve impulses and muscle movement.

Ambenonium is used to treat the symptoms of myasthenia gravis.

Ambenonium may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Mytelase Chloride (ambenonium)?

You should not use this medication if you are allergic to ambenonium, or if you are using certain medications.

Be sure your doctor knows if you use: mecamylamine, (Inversine), atropine (Atreza, Donnatal, Sal-Tropine, Lomotil, Lomocot, and others), blood pressure medications, or a diuretic (water pill).

Before using ambenonium, tell your doctor if you have asthma, Parkinson’s disease, or a bladder or bowel obstruction.

Your doctor may occasionally change your dose to make sure you get the best results from this medication. You may be asked to keep a daily record of when you took each dose and how long the effects lasted. This will help your doctor determine if your dose needs to be adjusted.

What should I discuss with my health care provider before taking Mytelase Chloride (ambenonium)?

You should not use this medication if you are allergic to ambenonium, or if you are using certain medications. Be sure your doctor knows if you use:

mecamylamine, (Inversine);

atropine (Atreza, Donnatal, Sal-Tropine, Lomotil, Lomocot, and others);

blood pressure medications; or

a diuretic (water pill).

Before using ambenonium, tell your doctor if you are allergic to any drugs, or if you have:

asthma;

Parkinson’s disease; or

a bladder or bowel obstruction.

If you have any of these conditions, you may need a dose adjustment or special tests during treatment.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether ambenonium passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Mytelase Chloride (ambenonium)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

This medication is usually given every 3 or 4 hours during the day. Follow your doctor’s instructions.

Your doctor may occasionally change your dose to make sure you get the best results from this medication. You may be asked to keep a daily record of when you took each dose and how long the effects lasted. This will help your doctor determine if your dose needs to be adjusted.

Store ambenonium at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include severe diarrhea, muscle twitching, anxiety, sweating, and cough or breathing problems.

What should I avoid while taking Mytelase Chloride (ambenonium)?

There are no restrictions on food, beverages, or activity while using ambenonium unless your doctor has told you otherwise.

Mytelase Chloride (ambenonium) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

severe diarrhea;

muscle twitching; or

cough with sputum (mucus).

Less serious side effects may include:

sweating or urinating more than usual;

drooling, watery eyes;

warmth or tingly feeling;

nausea, vomiting, stomach pain;

blurred vision;

anxiety;

dizziness, spinning feeling; or

muscle cramps.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Mytelase Chloride (ambenonium)?

Before taking ambenonium, tell your doctor if you are taking any form of belladonna. You may not be able to use ambenonium, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can interact with ambenonium. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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Mytelase

Posted by admin on November 5th, 2009

Mytelase

Mytelase is used for:

Treating myasthenia gravis. It may also be used for other conditions as determined by your doctor.

Mytelase is a cholinesterase inhibitor. It works by improving nerve impulses in muscles so that the muscles are better able to work.

Do NOT use Mytelase if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Mytelase :

Some medical conditions may interact with Mytelase . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Mytelase . Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Mytelase may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Mytelase :

Use Mytelase as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Mytelase .

Important safety information:

Possible side effects of Mytelase :

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); diarrhea; fainting; increased production of saliva; increased sweating; muscle weakness; nausea; small pupils; stomach cramps; tremor; trouble speaking or swallowing; vision changes; vomiting; weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Store Mytelase at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Mytelase out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Mytelase . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Mytelase resources

Posted in cholinergic muscle stimulants Tags: , No Comments »

Mestinon Timespan

Posted by admin on November 5th, 2009

Mestinon Timespan

Generic Name: pyridostigmine (py rid o STIG meen)

What is Mestinon Timespan (pyridostigmine)?

Pyridostigmine affects chemicals in the body that are involved in the communciation between nerve impulses and muscle movement.

Pyridostigmine is used to treat the symptoms of myasthenia gravis. It is also used in military personnel who have been exposed to nerve gas.

Pyridostigmine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Mestinon Timespan (pyridostigmine)?

Do not use pyridostigmine if you have a serious stomach condition called peritonitis, or if you have a bladder or bowel obstruction.

Before using pyridostigmine, tell your doctor if you have asthma or kidney disease.

The amount and timing of this medicine is extremely important to the success of your treatment. Carefully follow your doctor’s instructions about how much medicine to take and when to take it.

Your doctor may occasionally change your dose to make sure you get the best results from this medication. You may be asked to keep a daily record of when you took each dose and how long the effects lasted. This will help your doctor determine if your dose needs to be adjusted.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking pyridostigmine. You may need to stop using the medicine for a short time.

What should I discuss with my health care provider before taking Mestinon Timespan (pyridostigmine)?

Do not use pyridostigmine if you have a bladder or bowel obstruction.

Before using pyridostigmine, tell your doctor if you have:

asthma; or

kidney disease;

If you have any of these conditions, you may not be able to use pyridostigmine, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether pyridostigmine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Mestinon Timespan (pyridostigmine)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of pyridostigmine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

The amount and timing of this medicine is extremely important to the success of your treatment. Carefully follow your doctor’s instructions about how much medicine to take and when to take it.

Your doctor may occasionally change your dose to make sure you get the best results from this medication. You may be asked to keep a daily record of when you took each dose and how long the effects lasted. This will help your doctor determine if your dose needs to be adjusted.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking pyridostigmine. You may need to stop using the medicine for a short time.

Store pyridostigmine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Symptoms of a pyridostigmine overdose may include extreme muscle weakness, nausea, vomiting, diarrhea, sweating, and muscle cramps, or weakness.

What should I avoid while taking Mestinon Timespan (pyridostigmine)?

There are no restrictions on food, beverages, or activity while using pyridostigmine unless your doctor has told you otherwise.

Mestinon Timespan (pyridostigmine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

extreme muscle weakness;

severe vomiting or diarrhea;

vision problems; or

muscle cramps or twitching.

Other less serious side effects are more likely to occur, such as:

sweating or urinating more than usual;

drooling, watery eyes;

warmth or tingly feeling;

mild nausea, vomiting, or stomach pain;

mild itching or skin rash; or

muscle or joint pain.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Mestinon Timespan (pyridostigmine)?

Before taking pyridostigmine, tell your doctor if you are using any of the following drugs:

atropine (Donnatal, and others);

belladonna;

clidinium (Quarzan);

dicyclomine (Bentyl);

glycopyrrolate (Robinul);

hyoscyamine (Anaspaz, Cystospaz, Levsin);

mepenzolate (Cantil);

methantheline (Provocholine);

methscopolamine (Pamine);

propantheline (Pro-Banthine);

scopolamine (Transderm-Scop);

antibiotics such as neomycin (Mycafradin, Neo-Tab), kanamycin (Kantrex), or streptomycin; or

heart rhythm medications such as quinidine (Quinidex, Quinaglute), procainamide (Procan, Pronestyl), disopyramide (Norpace), mexiletine (Mexitil), tocainide (Tonocard), flecainide (Tambocor), propafenone (Rythmol), esmolol (Brevibloc), propranolol (Inderal), metoprolol (Toprol), amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), sotalol (Betapace).

If you are using any of these drugs, you may not be able to use pyridostigmine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect pyridostigmine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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Guanidine Hydrochloride

Posted by admin on November 5th, 2009

Guanidine HCl

Generic Name: guanidine (GWAN ih deen)

What is Guanidine HCl (guanidine)?

Guanidine improves the action of a chemical in the body that regulates muscle cells.

Guanidine is used to treat muscle weakness caused by Eaton-Lambert syndrome. Guanidine will not treat myasthenia gravis.

Guanidine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Guanidine HCl (guanidine)?

Before taking this medication, tell your doctor if you have bone marrow depression or a weak immune system.

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Guanidine can lower the blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. To be sure your blood cells do not get too low, your blood will need to be tested on a regular basis. Your urine may also need to be tested. It is important that you not miss any scheduled visits to your doctor.

What should I discuss with my health care provider before taking Guanidine HCl (guanidine)?

Before using this medication, tell your doctor if you have:

bone marrow depression; or

a weak immune system.

If you have any of these conditions, you may not be able to use guanidine, or you may need a dosage adjustment or special tests during treatment.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Guanidine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Guanidine HCl (guanidine)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Guanidine can lower the blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. To be sure your blood cells do not get too low, your blood will need to be tested on a regular basis. Your urine may also need to be tested. It is important that you not miss any scheduled visits to your doctor.

Store guanidine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a guanidine overdose may include loss of appetite, diarrhea, numbness or tingling of the lips and fingers, nervousness, tremors, severe muscle spasms or twitching, diarrhea, and vomiting.

What should I avoid while taking Guanidine HCl (guanidine)?

Avoid contact with people who have colds, the flu, or other contagious illnesses. Contact your doctor immediately if you develop signs of infection.

Do not receive a vaccine while you are being treated with guanidine. Vaccines may not work as well during your treatment with guanidine.

Guanidine HCl (guanidine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

easy bruising or bleeding, unusual weakness;

fever, chills, body aches, flu symptoms;

unusual thoughts, changes in behavior;

feeling light-headed, fainting;

confusion, hallucinations (seeing things that are not there);

weakness, lack of coordination;

numbness, coldness, or tingling in your face, lips, hands, or feet; or

fast or pounding heartbeats.

Other less serious side effects are more likely to occur, such as:

nausea, loss of appetite, diarrhea, stomach pain;

skin rash;

increased sweating; or

dry mouth, dry flaky skin.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Guanidine HCl (guanidine)?

Before taking guanidine, tell your doctor if you are using any of the following drugs:

a steroid medicine;

cancer chemotherapy or radiation;

cyclosporine (Neoral, Sandimmune, Gengraf);

etanercept (Enbrel), efalizumab (Raptiva), tacrolimus (Prograf), sirolimus (Rapamune); or

any other medicines that can weaken your immune system.

If you are using any of these drugs, you may not be able to use guanidine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect guanidine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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Enlon-Plus

Posted by admin on November 5th, 2009

Enlon-Plus

Enlon-Plus Description

Enlon-Plus – Clinical Pharmacology

Pharmacodynamics

Pharmacokinetics

Table of Pharmacokinetic Values for Edrophonium Chloride

Indications and Usage for Enlon-Plus

Contraindications

Warnings

Precautions

General

Drug Interactions

Pregnancy Category C

Labor and Delivery

Nursing Mothers

Pediatric Use

Geriatric Use

Adverse Reactions

Cardiovascular

Cardiovascular

Respiratory

Neurologic

Gastrointestinal

Musculoskeletal

Miscellaneous

Overdosage

Enlon-Plus Dosage and Administration

How is Enlon-Plus Supplied

REFERENCES

More Enlon-Plus resources

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Enlon

Posted by admin on November 5th, 2009

Enlon

Generic Name: edrophonium (ED roe FOE nee um)

What is Enlon (edrophonium)?

Edrophonium is used as part of a medical test to help diagnose a muscle disorder called myasthenia gravis.

Edrophonium is sometimes used to reverse the effects of certain medications used to prevent muscle contractions during surgical procedures.

Edrophonium may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Enlon (edrophonium)?

You should not receive this medication if you are allergic to edrophonium, or have a blockage in your intestines or obstructed urine flow.

Before you receive edrophonium, tell your doctor if you have asthma, a heart rhythm disorder, or if you are allergic to sulfites. Also tell your doctor if you are pregnant or breast-feeding.

Tell your caregivers at once if you have a serious side effect such as slow heart rate, chest pain, weak pulse, fainting, weak or shallow breathing, increased urination, seizures, or trouble swallowing.

Less serious side effects may occur (some of which can be expected as part of a positive test reaction to edrophonium) such as watery eyes, vision problems, changes in your voice, mild nausea, vomiting, stomach pain, weakness, or muscle twitching.

What should I discuss with my health care provider before receiving Enlon (edrophonium)?

You should not receive this medication if you are allergic to edrophonium, or have certain conditions. Be sure your doctor knows if you have:

a blockage in your intestines; or

obstructed urine flow.

Before you receive edrophonium, tell your doctor if you are allergic to any drugs, or if you have:

asthma;

a heart rhythm disorder; or

if you are allergic to sulfites.

If you have any of these conditions, you may need a dose adjustment or special tests to safely receive edrophonium.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant before you receive edrophonium. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is edrophonium given?

Edrophonium is given as an injection through a needle placed into a muscle or vein. You will receive this injection in a clinic or hospital setting as part of a medical test.

When used in diagnosing myasthenia gravis, edrophonium is given in small doses over 15 to 45 seconds. After each dose you will be observed for the expected reaction to this medication (muscle twitching, vision changes, increased muscle weakness, sweating, stomach cramps, nausea, and other symptoms). You may receive other medications to treat the reaction to edrophonium.

The test you are receiving may be repeated a second time.

Your specific edrophonium test may be performed in a different manner than described above.

What happens if I miss a dose?

Since edrophonium is given by a healthcare professional, it is not likely that you will miss a dose.

What happens if I overdose?

Tell your caregivers right away if you think you have received too much of this medicine.

Overdose symptoms may include nausea, vomiting, diarrhea, sweating, slow heart rate, and increased salivation (drooling).

What should I avoid after receiving Enlon (edrophonium)?

Follow your doctor’s instructions about any restrictions on food, beverages, or activity after you have been treated with edrophonium.

Enlon (edrophonium) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Tell your caregivers at once if you have a serious side effect such as:

slow heart rate;

chest pain, weak pulse, increased sweating, and dizziness;

feeling like you might pass out;

weak or shallow breathing;

urinating more than usual;

seizures (convulsions); or

trouble swallowing.

Less serious side effects (some of which can be expected as part of a positive test reaction) may include:

watery eyes, vision problems;

changes in your voice;

mild nausea, vomiting, diarrhea, stomach pain;

weakness; or

muscle twitching.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Enlon (edrophonium)?

There may be other drugs that can interact with edrophonium. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

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