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Archive for the ‘antiemetic’ Category

Marezine

Posted by admin on November 4th, 2009

Marezine

Marezine is used for:

Preventing and treating nausea, vomiting, and dizziness associated with motion sickness. It may also be used for other conditions as determined by your doctor.

Marezine is an anticholinergic. It works by blocking a chemical messenger in the brain, which helps to reduce or prevent vomiting.

Do NOT use Marezine if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Marezine :

Some medical conditions may interact with Marezine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Marezine . Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Marezine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Marezine :

Use Marezine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Marezine .

Important safety information:

Possible side effects of Marezine :

All medicines may cause side effects, but many people have no, or minor, side effects.

Drowsiness; dry mouth.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Store Marezine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Marezine out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Marezine . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Marezine resources

Compare Marezine with other medications for the treatment of:

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Granisol

Posted by admin on November 4th, 2009

Granisol

Generic Name: granisetron (oral) (gra NIS e tron)

What is granisetron?

Granisetron blocks the actions of chemicals in the body that may cause nausea and vomiting.

Granisetron is used to prevent nausea and vomiting caused by cancer chemotherapy or radiation therapy, and anesthesia used during surgery.

Granisetron may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about granisetron?

You should not use this medication if you are allergic to granisetron.

Before taking granisetron, tell your doctor if you have recently had stomach or intestinal surgery. You may need a dose adjustment or special tests to safely take granisetron.

Do not take granisetron on the days you do not have chemotherapy, unless your doctor has told you to.

What should I discuss with my healthcare provider before taking granisetron?

You should not use this medication if you are allergic to granisetron.

Before taking granisetron, tell your doctor if you have recently had stomach or intestinal surgery. You may need a dose adjustment or special tests to safely take granisetron.

FDA pregnancy category B. Granisetron is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether granisetron passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to anyone younger than 18 years old without a doctor’s advice.

How should I take granisetron?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Take each oral dose with a full glass of water.

Granisetron is usually taken up to 1 hour before chemotherapy or radiation starts. If you are taking this medication with chemotherapy, you may need to take a second granisetron dose 12 hours after your first dose. Follow your doctor’s instructions.

Do not take granisetron on the days you do not have chemotherapy, unless your doctor has told you to.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Store granisetron at room temperature away from moisture, heat, and light. Keep the bottle of liquid medicine tightly closed and in an upright position when not in use.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of granisetron is not expected to produce life-threatening side effects.

What should I avoid while taking granisetron?

Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using granisetron.

Granisetron side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using granisetron and call your doctor at once if you have a serious side effect such as:

chest pain, uneven heart rate;

pale skin, easy bruising or bleeding; or

feeling like you might pass out.

Less serious side effects may include:

headache;

diarrhea or constipation;

nausea, vomiting, stomach pain or upset;

loss of appetite;

drowsiness, weakness;

dizziness, anxiety;

sleep problems (insomnia); or

temporary hair loss.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect granisetron?

There may be other drugs that can interact with granisetron. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

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Sancuso

Posted by admin on November 4th, 2009

Sancuso

Generic Name: granisetron (transdermal) (gra NIS e tron)

What is Sancuso?

Sancuso blocks the actions of chemicals in the body that may cause nausea and vomiting.

Sancuso transdermal (skin patch) is used to prevent nausea and vomiting caused by cancer chemotherapy.

Sancuso may also be used for other purposes not listed in this medication guide.

Important information about Sancuso

You should not use Sancuso if you are allergic to granisetron.

Before using Sancuso, tell your doctor if you have a stomach or intestinal disorder, if you have recently had stomach or intestinal surgery, or if you have ever had an allergic reaction to any type of medicated skin patch. You may need a dose adjustment or special tests to safely use Sancuso.

Avoid exposing the skin patch or your upper arm to sunlight, sunlamps, or tanning beds. Natural or artificial sunlight can cause a skin reaction where the Sancuso skin patch is worn. This effect may last for up to 10 days after the patch is removed. Wear protective clothing over your arms while you are wearing the skin patch and for at least 10 days after you remove a patch. Do not use Sancuso during a time when you are not having chemotherapy, unless your doctor has told you to.

What should I discuss with my healthcare provider before using Sancuso?

You should not use Sancuso if you are allergic to granisetron.

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before using Sancuso, tell your doctor if you have:

a stomach or intestinal disorder;

if you have recently had stomach or intestinal surgery; or

if you have ever had an allergic reaction to any type of medicated skin patch.

How should I use Sancuso?

Use Sancuso exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Apply the Sancuso skin patch 24 to 48 hours before your chemotherapy is scheduled to start. To use the patch, open the sealed pouch and remove the protective liner. Apply the transdermal patch to a clean, dry area on the outer side of your upper arm. Avoid placing the patch on skin that is red, irritated or damaged.

Press the patch onto the skin and press it down firmly with your fingers. Make sure the patch is well sealed around the edges.

Leave the patch in place and wear it for at least 24 hours after your chemotherapy ends. You may continue wearing the Sancuso skin patch for up to 7 days if needed, depending on your chemotherapy schedule. Follow your doctor’s instructions.

Do not cut or trim the Sancuso skin patch.

If the patch falls off, try sticking it back on. If it does not stay on, replace it with a new one and wear it for the rest of your patch-wearing time. Do not change your schedule, even if you apply a new patch to replace one that has fallen off.

After removing a patch, fold it in half so it sticks together and throw it away in a place where children or pets cannot get to it.

Do not use Sancuso during a time when you are not having chemotherapy, unless your doctor has told you to. Keep each Sancuso skin patch in its sealed pouch until you are ready to use it. Store the pouches at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Call your doctor for instructions if you forget to apply a Sancuso skin patch at least 24 hours before your chemotherapy is scheduled to start. Do not use extra patches to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of Sancuso is not expected to produce life-threatening side effects.

What should I avoid while using Sancuso?

Avoid exposing the Sancuso skin patch or your upper arm to sunlight, sunlamps, or tanning beds. Natural or artificial sunlight can cause a skin reaction where the Sancuso skin patch is worn. This effect may last for up to 10 days after the patch is removed. Wear protective clothing over your arms while you are wearing the skin patch and for at least 10 days after you remove a patch.

Sancuso side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Remove the skin patch and call your doctor at once if you have a serious side effect such as:

severe redness, itching, swelling, or other irritation where the patch is worn;

uneven heart rate;

fever, pale skin, easy bruising or bleeding; or

feeling like you might pass out.

Less serious Sancuso side effects may include:

diarrhea, constipation;

nausea, vomiting, stomach pain;

loss of appetite;

headache;

mild itching or skin irritation where the patch is worn;

dizziness, drowsiness, anxiety;

sleep problems (insomnia); or

temporary hair loss.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Sancuso?

There may be other drugs that can interact with Sancuso. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

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Zofran

Posted by admin on November 4th, 2009

Zofran

Generic Name: ondansetron (on DAN se tron)

What is Zofran?

Zofran blocks the actions of chemicals in the body that can trigger nausea and vomiting.

Zofran is used to prevent nausea and vomiting that may be caused by surgery or by medicine to treat cancer (chemotherapy or radiation).

Zofran may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Zofran?

Do not use this medication if you are allergic to ondansetron or to similar medicines such as dolasetron (Anzemet), granisetron (Kytril), or palonosetron (Aloxi).

Before taking Zofran, tell your doctor if you have liver disease, or a personal or family history of Long QT syndrome.

Zofran orally disintegrating tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).

The serious side effects of this medication include blurred vision or temporary blindness, slow heart rate, trouble breathing, anxiety, agitation, shivering, feeling light-headed, or fainting, and urinating less than usual or not at all. Stop taking Zofran and call your doctor at once if you have any of these side effects. Zofran can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What should I discuss with my health care provider before taking Zofran?

Do not use this medication if you are allergic to ondansetron, to similar medicines such as dolasetron (Anzemet), granisetron (Kytril), or palonosetron (Aloxi).

Before taking Zofran, tell your doctor if you are allergic to any drugs, or if you have:

a history of allergic reaction to any medicine; or

a personal or family history of Long QT syndrome.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take Zofran.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Zofran can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Zofran orally disintegrating tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).

How should I take Zofran?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Zofran can be taken with or without food.

Take the Zofran regular tablet with a full glass of water.

To take Zofran orally disintegrating tablet:

Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.

Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away.

Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet.

Measure the liquid form of Zofran with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Store Zofran at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have received too much of this medicine.

Overdose symptoms may include sudden loss of vision, severe constipation, feeling light-headed, or fainting.

What should I avoid while taking Zofran?

Zofran can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Zofran side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

blurred vision or temporary blindness;

fever;

slow heart rate, trouble breathing;

anxiety, agitation, shivering;

feeling light-headed, fainting; or

urinating less than usual or not at all.

Less serious side effects may include:

diarrhea or constipation;

weakness or tired feeling;

headache;

dizziness or drowsiness;

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Zofran?

Before receiving Zofran, tell your doctor if you are using any of the following drugs:

phenytoin (Dilantin), phenobarbital (Luminal);

carbamazepine (Carbatrol, Tegretol);

tramadol (Ultram); or

rifampin (Rifadin, Rimactane, Rifater).

This list is not complete and there may be other drugs that can interact with Zofran. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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Zofran ODT

Posted by admin on November 4th, 2009

Zofran ODT Orally Disintegrating Tablets

Zofran ODT Orally Disintegrating Tablets are used for:

Preventing nausea and vomiting due to chemotherapy, radiation treatment, or surgery. It may also be used for other conditions as determined by your doctor.

Zofran ODT Orally Disintegrating Tablets are a serotonin 5-HT

Do NOT use Zofran ODT Orally Disintegrating Tablets if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zofran ODT Orally Disintegrating Tablets:

Some medical conditions may interact with Zofran ODT Orally Disintegrating Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Zofran ODT Orally Disintegrating Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Zofran ODT Orally Disintegrating Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Zofran ODT Orally Disintegrating Tablets:

Use Zofran ODT Orally Disintegrating Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Zofran ODT Orally Disintegrating Tablets.

Important safety information:

Possible side effects of Zofran ODT Orally Disintegrating Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects.

Constipation; diarrhea; dizziness; drowsiness; headache; tiredness; weakness.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fever; skin tingling or numbness; trouble urinating; vision change or loss.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Store Zofran ODT Orally Disintegrating Tablets between 36 and 86 degrees F (2 and 30 degrees C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Zofran ODT Orally Disintegrating Tablets out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Zofran ODT Orally Disintegrating Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Zofran ODT Orally Disintegrating Tablets resources

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Kytril

Posted by admin on November 4th, 2009

Kytril

Generic Name: granisetron (oral) (gra NIS e tron)

What is Kytril?

Kytril blocks the actions of chemicals in the body that may cause nausea and vomiting.

Kytril is used to prevent nausea and vomiting caused by cancer chemotherapy or radiation therapy, and anesthesia used during surgery.

Kytril may also be used for other purposes not listed in this medication guide.

Important information about Kytril

You should not use Kytril if you are allergic to granisetron.

Before taking Kytril, tell your doctor if you have recently had stomach or intestinal surgery. You may need a dose adjustment or special tests to safely take this medicine.

Do not take Kytril on the days you do not have chemotherapy, unless your doctor has told you to.

What should I discuss with my healthcare provider before taking Kytril?

You should not use Kytril if you are allergic to granisetron.

Before taking Kytril, tell your doctor if you have recently had stomach or intestinal surgery. You may need a dose adjustment or special tests to safely take Kytril.

FDA pregnancy category B. Kytril is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Kytril passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to anyone younger than 18 years old without a doctor’s advice.

How should I take Kytril?

Take Kytril exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Take each oral dose with a full glass of water.

Kytril is usually taken up to 1 hour before chemotherapy or radiation starts. If you are taking this medication with chemotherapy, you may need to take a second Kytril dose 12 hours after your first dose. Follow your doctor’s instructions.

Do not take Kytril on the days you do not have chemotherapy, unless your doctor has told you to.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Store Kytril at room temperature away from moisture, heat, and light. Keep the bottle of liquid medicine tightly closed and in an upright position when not in use.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of Kytril is not expected to produce life-threatening side effects.

What should I avoid while taking Kytril?

Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using Kytril.

Kytril side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Kytril and call your doctor at once if you have a serious side effect such as:

chest pain, uneven heart rate;

pale skin, easy bruising or bleeding; or

feeling like you might pass out.

Less serious Kytril side effects may include:

headache;

diarrhea or constipation;

nausea, vomiting, stomach pain or upset;

loss of appetite;

drowsiness, weakness;

dizziness, anxiety;

sleep problems (insomnia); or

temporary hair loss.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Kytril?

There may be other drugs that can interact with Kytril. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

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Anzemet

Posted by admin on November 4th, 2009

Anzemet

Generic Name: dolasetron (doe LAH seh tron)

What is Anzemet?

Anzemet blocks the actions of chemicals in the body that may cause nausea and vomiting.

Anzemet is used to prevent nausea and vomiting associated with cancer chemotherapy or surgery. It may also be used to prevent and treat nausea and vomiting after surgery.

Anzemet may also be used for purposes other than those listed in this medication guide.

Important information about Anzemet

Do not take Anzemet without first talking to your doctor if you have heart problems or if you take other medicines. Anzemet can affect the way that your heart beats, which can be dangerous.

Who should not take Anzemet?

Do not take this medication without first talking to your doctor if you:

have low levels of potassium in your blood;

have low levels of magnesium in your blood;

are taking a diuretic (water pill);

have a history of congenital QT syndrome; or

are taking a medicine to treat an irregular heartbeat.

Anzemet may affect your heart, especially if you have any of the conditions or are taking any of the medicines listed above.

Anzemet is in the FDA pregnancy category B. This means that it is not expected to harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or if you are planning a pregnancy. It is not known whether this medication passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take Anzemet?

Take Anzemet exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take the tablets with a full glass of water.

The injectable form of Anzemet is intended for intravenous use. However, it can also be used orally when mixed with apple or apple-grape juice as directed by your doctor. The mixture of Anzemet and juice is good for up to 2 hours at room temperature.

Anzemet can be taken with or without food.

Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a Anzemet overdose are not well known but might include tremors, seizures, and heart problems.

What should I avoid while taking Anzemet?

There are no restrictions on foods, beverages, or activities during treatment with this medication unless otherwise directed by your doctor.

Anzemet side effects

If you experience any of the following uncommon but serious side effects, stop taking Anzemet and seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

irregular heartbeats; or

muscle cramps or uncontrollable movements.

Other, less serious side effects may be more likely to occur. Continue to take Anzemet and talk to your doctor if you experience

headache;

fatigue, drowsiness, or dizziness; or

diarrhea.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Anzemet?

Do not take Anzemet without first talking to your doctor if you are taking any of the following medicines:

a diuretic (water pill) such as furosemide (Lasix), bumetanide (Bumex), torsemide (Demadex), chlorothiazide (Diuril), hydrochlorothiazide (HCTZ, HydroDiuril, Esidrix, Microzide, Oretic), chlorthalidone (Hygroton, Thalitone), indapamide (Lozol), metolazone (Mykrox, Zaroxolyn), amiloride (Midamor), spironolactone (Aldactone, Spironol), triamterene (Dyrenium), and others;

a medicine to treat irregular heartbeats such as amiodarone (Cordarone), bepridil (Vascor), disopyramide (Norpace), sotalol (Betapace), and others;

cimetidine (Tagamet, Tagamet HB); or

rifampin (Rifadin, Rimactane) or rifabutin (Mycobutin).

You may not be able to take this medication, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with Anzemet. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines during treatment with Anzemet.

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Aloxi

Posted by admin on November 4th, 2009

Aloxi

Generic Name: palonosetron (PAL oh NOE se tron)

What is Aloxi?

Aloxi (palonosetron) blocks the actions of chemicals in the body that can trigger nausea and vomiting.

Aloxi is used to prevent nausea and vomiting that may be caused by surgery or by medicine to treat cancer (chemotherapy or radiation).

Aloxi may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Aloxi?

Do not use Aloxi if you are allergic to palonosetron.

Before you receive Aloxi, tell your doctor if you have an electrolyte imbalance, a personal or family history of “Long QT syndrome,” if you take a diuretic (water pill), or if you take a heart rhythm medication.

Tell your doctor if you have ever had an allergic reaction to dolasetron (Anzemet), granisetron (Kytril), or ondansetron (Zofran).

Call your doctor at once if you have uneven heartbeats while receiving Aloxi.

What should I discuss with my health care provider before receiving Aloxi?

You should not use Aloxi if you are allergic to palonosetron.

Before you receive Aloxi, tell your doctor if you have:

an electrolyte imbalance such as low levels of potassium or magnesium in your blood;

a personal or family history of “Long QT syndrome”;

if you are taking a diuretic (water pill);

if you are taking a heart rhythm medication; or

if you have ever had an allergic reaction to dolasetron (Anzemet), granisetron (Kytril), or ondansetron (Zofran).

If you have any of these conditions, you may not be able to use Aloxi, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category B. Aloxi is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Aloxi passes into breast milk or if it could harm a nursing baby. Do not use Aloxi without telling your doctor if you are breast-feeding a baby.

How is Aloxi given?

Aloxi is given as an injection through a needle placed into a vein. You will receive this injection in a hospital or cancer treatment setting.

Aloxi is usually given within 30 minutes before the start of your chemotherapy treatment.

What happens if I miss a dose?

Since Aloxi is given by a healthcare professional before your chemotherapy, it is not likely that you will miss a dose.

What happens if I overdose?

Seek emergency medical attention if you think you have received too much Aloxi.

Symptoms of a Aloxi overdose are not known.

What should I avoid after receiving Aloxi?

Follow your doctor’s instructions about any restrictions on food, beverages, or activity after you receive Aloxi.

Aloxi side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:.

fever;

slow or uneven heart rate, trouble breathing;

anxiety, agitation, shivering;

feeling light-headed, fainting; or

urinating less than usual or not at all.

Less serious side effects may include:

diarrhea;

constipation;

dizziness;

headache; or

tired feeling.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Aloxi?

Before receiving Aloxi, tell your doctor about all cancer medications you receive, or if you are using any of the following drugs:

a diuretic (water pill); or

heart rhythm medication such as amiodarone (Cordarone), bepridil (Vascor), disopyramide (Norpace), sotalol (Betapace), and others.

This list is not complete and there may be other drugs that can affect Aloxi. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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Sleep-ettes

Posted by admin on November 4th, 2009

Sleep-ettes

Generic Name: diphenhydramine (DYE fen HYE dra meen)

What is Sleep-ettes (diphenhydramine)?

Diphenhydramine is an antihistamine. Diphenhydramine blocks the effects of the naturally occurring chemical histamine in the body.

Diphenhydramine is used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.

Diphenhydramine is also used to suppress coughs, to treat motion sickness, to induce sleep, and to treat mild forms of Parkinson’s disease.

Diphenhydramine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Sleep-ettes (diphenhydramine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking diphenhydramine.

What should I discuss with my healthcare provider before taking Sleep-ettes (diphenhydramine)?

Do not take diphenhydramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

glaucoma or increased pressure in the eye;

a stomach ulcer;

an enlarged prostate, bladder problems or difficulty urinating;

an overactive thyroid (hyperthyroidism);

hypertension or any type of heart problems; or

asthma.

You may not be able to take diphenhydramine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Diphenhydramine is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take diphenhydramine without first talking to your doctor if you are pregnant. Infants are especially sensitive to the effects of antihistamines, and side effects could occur in a breast-feeding baby. Do not take diphenhydramine without first talking to your doctor if you are nursing a baby. If you are over 60 years of age, you may be more likely to experience side effects from diphenhydramine. You may require a lower dose of this medication.

How should I take Sleep-ettes (diphenhydramine)?

Take diphenhydramine exactly as directed on the package or as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Diphenhydramine can be taken with or without food.

For motion sickness, a dose is usually taken 30 minutes before motion, then with meals and at bedtime for the duration of exposure.

As a sleep aid, diphenhydramine should be taken approximately 30 minutes before bedtime.

To ensure that you get a correct dose, measure the liquid forms of diphenhydramine with a special dose-measuring spoon or cup, not with a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Never take more of this medication than is prescribed for you. The maximum amount of diphenhydramine that you should take in any 24-hour period is 300 mg.

Store diphenhydramine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a diphenhydramine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.

What should I avoid while taking Sleep-ettes (diphenhydramine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking diphenhydramine.

Sleep-ettes (diphenhydramine) side effects

Stop taking diphenhydramine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take diphenhydramine and talk to your doctor if you experience

sleepiness, fatigue, or dizziness;

headache;

dry mouth; or

difficulty urinating or an enlarged prostate.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Sleep-ettes (diphenhydramine)?

Do not take diphenhydramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Talk to your pharmacist before taking other over-the-counter cough, cold, allergy, or insomnia medications. These products may contain medicines similar to diphenhydramine, which could lead to an antihistamine overdose.

Before taking this medication, tell your doctor if you are taking any of the following medicines:

anxiety or sleep medicines such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril), or triazolam (Halcion);

medications for depression such as amitriptyline (Elavil), doxepin (Sinequan), nortriptyline (Pamelor), fluoxetine (Prozac), sertraline (Zoloft), or paroxetine (Paxil); or

any other medications that make you feel drowsy, sleepy, or relaxed.

Drugs other than those listed here may also interact with diphenhydramine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Posted in anticholinergic antiemetics Tags: , No Comments »

Sleep

Posted by admin on November 4th, 2009

Sleep

Generic Name: diphenhydramine (DYE fen HYE dra meen)

What is Sleep (diphenhydramine)?

Diphenhydramine is an antihistamine. Diphenhydramine blocks the effects of the naturally occurring chemical histamine in the body.

Diphenhydramine is used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.

Diphenhydramine is also used to suppress coughs, to treat motion sickness, to induce sleep, and to treat mild forms of Parkinson’s disease.

Diphenhydramine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Sleep (diphenhydramine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking diphenhydramine.

What should I discuss with my healthcare provider before taking Sleep (diphenhydramine)?

Do not take diphenhydramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

glaucoma or increased pressure in the eye;

a stomach ulcer;

an enlarged prostate, bladder problems or difficulty urinating;

an overactive thyroid (hyperthyroidism);

hypertension or any type of heart problems; or

asthma.

You may not be able to take diphenhydramine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Diphenhydramine is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take diphenhydramine without first talking to your doctor if you are pregnant. Infants are especially sensitive to the effects of antihistamines, and side effects could occur in a breast-feeding baby. Do not take diphenhydramine without first talking to your doctor if you are nursing a baby. If you are over 60 years of age, you may be more likely to experience side effects from diphenhydramine. You may require a lower dose of this medication.

How should I take Sleep (diphenhydramine)?

Take diphenhydramine exactly as directed on the package or as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Diphenhydramine can be taken with or without food.

For motion sickness, a dose is usually taken 30 minutes before motion, then with meals and at bedtime for the duration of exposure.

As a sleep aid, diphenhydramine should be taken approximately 30 minutes before bedtime.

To ensure that you get a correct dose, measure the liquid forms of diphenhydramine with a special dose-measuring spoon or cup, not with a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Never take more of this medication than is prescribed for you. The maximum amount of diphenhydramine that you should take in any 24-hour period is 300 mg.

Store diphenhydramine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a diphenhydramine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.

What should I avoid while taking Sleep (diphenhydramine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking diphenhydramine.

Sleep (diphenhydramine) side effects

Stop taking diphenhydramine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take diphenhydramine and talk to your doctor if you experience

sleepiness, fatigue, or dizziness;

headache;

dry mouth; or

difficulty urinating or an enlarged prostate.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Sleep (diphenhydramine)?

Do not take diphenhydramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Talk to your pharmacist before taking other over-the-counter cough, cold, allergy, or insomnia medications. These products may contain medicines similar to diphenhydramine, which could lead to an antihistamine overdose.

Before taking this medication, tell your doctor if you are taking any of the following medicines:

anxiety or sleep medicines such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril), or triazolam (Halcion);

medications for depression such as amitriptyline (Elavil), doxepin (Sinequan), nortriptyline (Pamelor), fluoxetine (Prozac), sertraline (Zoloft), or paroxetine (Paxil); or

any other medications that make you feel drowsy, sleepy, or relaxed.

Drugs other than those listed here may also interact with diphenhydramine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Posted in anticholinergic antiemetics Tags: , No Comments »
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