Archive for the ‘anorexiants’ Category

Adipex-P

Adipex-P

Adipex-P is used for:

Reducing weight in obese patients when used short-term and combined with exercise, diet, and behavioral modification.

Adipex-P is an appetite suppressant. It works by helping to release certain chemicals in the brain that control appetite.

Do NOT use Adipex-P if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Adipex-P :

Some medical conditions may interact with Adipex-P . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Adipex-P . Tell your health care provider if you are taking any other medicines, especially any of the following:

Ask your health care provider if Adipex-P may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Adipex-P :

Use Adipex-P as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Adipex-P .

Important safety information:

After you have taken Adipex-P for a few weeks, it will usually not work as well as when you began taking it. This is known at TOLERANCE. Talk with your doctor if Adipex-P stops working well. Do not take more medicine than prescribed.

Some people who use Adipex-P for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you stop taking Adipex-P suddenly, you may have WITHDRAWAL symptoms. These may include extreme tiredness, mental depression, trouble sleeping, irritability, or mental, mood, or personality changes.

Possible side effects of Adipex-P :

All medicines may cause side effects, but many people have no, or minor, side effects.

Bad taste in mouth; changes in sex drive; constipation; diarrhea; difficulty sleeping; dizziness; dry mouth; exaggerated sense of well being; headache; impotence; nervousness; overstimulation; restlessness; sleeplessness; upset stomach.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bizarre behavior; chest pain; fainting; fast heartbeat; pounding in the chest; shortness of breath; swelling of the legs and feet; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Store Adipex-P at room temperature, between 59 and 77 degrees F (15 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Adipex-P out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Adipex-P . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Adipex-P resources

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Bontril Slow Release

Bontril Slow Release

Generic Name: phendimetrazine (fen di MEH tra zeen)

What is Bontril Slow Release (phendimetrazine)?

Phendimetrazine is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an “anorectic” or “anorexigenic” drug. Phendimetrazine stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.

Phendimetrazine is used as a short-term supplement to diet and exercise in the treatment of obesity.

Phendimetrazine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Bontril Slow Release (phendimetrazine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Phendimetrazine may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities. Phendimetrazine is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually. Do not crush, chew, or open any “once-daily” phendimetrazine tablets or capsules. Swallow them whole.

What should I discuss with my healthcare provider before taking Bontril Slow Release (phendimetrazine)?

You cannot take phendimetrazine if you

have heart disease or high blood pressure;

have arteriosclerosis (hardening of the arteries);

have glaucoma;

have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days; or

have a history of drug or alcohol abuse.

Before taking this medication, tell your doctor if you have

problems with your thyroid,

an anxiety disorder,

epilepsy or another seizure disorder, or

diabetes.

You may not be able to take phendimetrazine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

It is not known whether phendimetrazine will harm an unborn baby. Do not take phendimetrazine without first talking to your doctor if you are pregnant. It is also not known whether phendimetrazine passes into breast milk. Do not take phendimetrazine without first talking to your doctor if you are breast-feeding a baby.

How should I take Bontril Slow Release (phendimetrazine)?

Take phendimetrazine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Phendimetrazine is usually taken once a day (sustained release formula) or two to three times daily (immediate-release formula) before meals on an empty stomach.

Do not take phendimetrazine in the evening because it may cause insomnia.

Do not crush, chew, or open any “once-daily” phendimetrazine tablets or capsules. Swallow them whole. Never take more of this medication than is prescribed for you. Too much phendimetrazine could be very dangerous to your health. Store phendimetrazine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose or if it is already evening, skip the missed dose and take only your next regularly scheduled dose. A dose taken too late in the day will cause insomnia. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a phendimetrazine overdose include restlessness, tremor, rapid breathing, confusion, hallucinations, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures.

What should I avoid while taking Bontril Slow Release (phendimetrazine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Phendimetrazine may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities.

Do not take phendimetrazine late in the day. A dose taken too late in the day can cause insomnia.

Bontril Slow Release (phendimetrazine) side effects

If you experience any of the following serious side effects, stop taking phendimetrazine and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

an irregular heartbeat or very high blood pressure (severe headache, blurred vision); or

hallucinations, abnormal behavior, or confusion.

Other, less serious side effects may be more likely to occur. Continue to take phendimetrazine and talk to your doctor if you experience

restlessness or tremor,

nervousness or anxiety,

headache or dizziness,

insomnia,

dry mouth or an unpleasant taste in your mouth,

diarrhea or constipation, or

impotence or changes in your sex drive.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Bontril Slow Release (phendimetrazine)?

You cannot take phendimetrazine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days.

Changes in insulin and other diabetes drug therapies may be necessary during treatment with phendimetrazine.

Phendimetrazine may reduce the effects of guanethidine (Ismelin). This could lead to an increase in blood pressure. Tell your doctor if you are taking guanethidine.

Before taking this medication, tell your doctor if you are taking a tricyclic antidepressant such as amitriptyline (Elavil), amoxapine (Asendin), doxepin (Sinequan), nortriptyline (Pamelor), imipramine (Tofranil), clomipramine (Anafranil), protriptyline (Vivactil), or desipramine (Norpramin). These drugs may decrease the effects of phendimetrazine.

Drugs other than those listed here may also interact with phendimetrazine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Desoxyn

Desoxyn

Desoxyn has a high risk for abuse. Long-term use of Desoxyn may lead to dependence. Use Desoxyn only as prescribed and do not share it with others.

Desoxyn is used for:

Treating attention deficit disorders with hyperactivity in children. It is also used on short-term basis (ie, a few weeks) in combination with other treatments to treat obesity. Desoxyn may also be used for other conditions as determined by your doctor.

Desoxyn is a central nervous system stimulant. The exact way it works is unknown. It controls the release of certain chemicals in the brain that affect mood, behavior, and appetite.

Do NOT use Desoxyn if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Desoxyn :

Some medical conditions may interact with Desoxyn . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Desoxyn . Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Desoxyn may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Desoxyn :

Use Desoxyn as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Desoxyn .

Important safety information:

When used for long periods of time or at high doses, Desoxyn may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Desoxyn stops working well. Do not take more than prescribed.

Some people who use Desoxyn for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction.

If you stop taking Desoxyn suddenly, you may have WITHDRAWAL symptoms. These may include severe tiredness, weakness, and mental depression.

Possible side effects of Desoxyn :

All medicines may cause side effects, but many people have no, or minor, side effects.

Constipation; diarrhea; dizziness; dry mouth; exaggerated sense of well-being; headache; loss of appetite; mild nervousness; nausea; upset stomach.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation or restlessness; blurred vision; change in sexual ability or desire; changes in speech; chest pain; difficulty moving; fast or irregular heartbeat; fever; mental/mood changes; pounding in chest; seizures; severe headaches; stomach pain; tremor; trouble sleeping; uncontrolled muscle movements (eg, tics); unusual weakness or tiredness; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Store Desoxyn at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep in a tightly closed container. Do not store in the bathroom. Keep Desoxyn out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Desoxyn . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Desoxyn resources

Compare Desoxyn with other medications for the treatment of:

Ionamin

Ionamin

Ionamin is used for:

Reducing weight in obese patients when used short-term and combined with exercise, diet, and behavioral modification.

Ionamin is an appetite suppressant. It works by helping to release certain chemicals in the brain that control appetite.

Do NOT use Ionamin if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ionamin :

Some medical conditions may interact with Ionamin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Ionamin . Tell your health care provider if you are taking any other medicines, especially any of the following:

Ask your health care provider if Ionamin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ionamin :

Use Ionamin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Ionamin .

Important safety information:

After you have taken Ionamin for a few weeks, it will usually not work as well as when you began taking it. This is known at TOLERANCE. Talk with your doctor if Ionamin stops working well. Do not take more medicine than prescribed.

Some people who use Ionamin for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you stop taking Ionamin suddenly, you may have WITHDRAWAL symptoms. These may include extreme tiredness, mental depression, trouble sleeping, irritability, or mental, mood, or personality changes.

Possible side effects of Ionamin :

All medicines may cause side effects, but many people have no, or minor, side effects.

Bad taste in mouth; constipation; diarrhea; difficulty sleeping; dizziness; dry mouth; exaggerated sense of well being; headache; nervousness; overstimulation; restlessness; sleeplessness; upset stomach.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bizarre behavior; changes in sex drive; chest pain; decreased sexual ability; fainting; fast or irregular heartbeat; mental or mood changes; pounding in the chest; shortness of breath; swelling of the legs and feet; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Store Ionamin at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ionamin out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Ionamin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Ionamin resources

Compare Ionamin with other medications for the treatment of:

Tenuate

Tenuate

diethylpropion (dye eth ill PROE pee on)

What is Tenuate?

Tenuate is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an “anorectic” or an “anorexigenic” drug. Tenuate stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.

Tenuate is used as a short-term supplement to diet and exercise in the treatment of obesity.

Tenuate may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Tenuate?

Use caution when driving, operating machinery, or performing other hazardous activities. Tenuate may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities.

Tenuate is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually.

Do not crush, chew, or open any “once-daily” Tenuate tablets or capsules. Swallow them whole.

Before taking Tenuate

You cannot take Tenuate if you

Before taking this medication, tell your doctor if you have

You may not be able to take Tenuate, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Tenuate is in the FDA pregnancy category B. This means that it is not expected to harm an unborn baby. Do not take Tenuate without first talking to your doctor if you are pregnant.

Tenuate passes into breast milk and may affect a nursing baby. Do not take Tenuate without first talking to your doctor if you are breast-feeding a baby.

>How should I take Tenuate?

Take Tenuate exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Take Tenuate on an empty stomach 1 hour before meals. An evening dose may be taken to overcome nighttime hunger.

Tenuate is usually taken three times a day (regular-release formula). Follow your doctor’s instructions.

The sustained-release formulation is usually taken once a day in the midmorning.

Do not crush, chew or open any “once-daily” (long-acting or sustained-release) diethylpropion tablets or capsules. Swallow them whole.

Never take more of this medication than is prescribed for you. Too much Tenuate could be very dangerous to your health.

Store Tenuate at room temperature away from moisture and heat.

>What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose or if it is already evening, skip the missed dose and take only your next regularly scheduled dose. A dose taken too late in the day will cause insomnia.

>What happens if I overdose?

Seek emergency medical attention.

Symptoms of a Tenuate overdose include restlessness, tremor, rapid breathing, confusion, hallucinations, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures.

>What should I avoid while taking Tenuate?

Use caution when driving, operating machinery, or performing other hazardous activities. Tenuate may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities.

>What are the possible side effects of Tenuate?

If you experience any of the following serious side effects, stop taking Tenuate and seek emergency medical attention:

Other, less serious side effects may be more likely to occur. Continue to take Tenuate and talk to your doctor if you experience

Tenuate is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

>What other drugs will affect Tenuate?

You cannot take Tenuate if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days.

Changes in insulin and other diabetes drug therapies may be necessary during treatment with Tenuate.

Tenuate may reduce the effects of guanethidine (Ismelin). This could lead to an increase in blood pressure. Tell your doctor if you are taking guanethidine.

Before taking this medication, tell your doctor if you are taking a tricyclic antidepressant such as amitriptyline (Elavil), amoxapine (Asendin), doxepin (Sinequan), nortriptyline (Pamelor), imipramine (Tofranil), clomipramine (Anafranil), protriptyline (Vivactil), or desipramine (Norpramin). These drugs may decrease the effects of Tenuate.

Drugs other than those listed here may also interact with Tenuate. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

>Where can I get more information?

Your pharmacist has more information about Tenuate written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (’Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2009 Cerner Multum, Inc. Version: 3.02. Revision Date: 07/02/2009 1:22:37 PM.

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Zantryl

Zantryl

Generic Name: phentermine (FEN ter meen)

What is Zantryl (phentermine)?

Phentermine is a stimulant that is similar to an amphetamine. Phentermine is an appetite suppressant that affects the central nervous system.

Phentermine is used togther with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes.

Phentermine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Zantryl (phentermine)?

Taking phentermine together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take phentermine with any other diet medications without your doctor’s advice.

Phentermine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of phentermine. Phentermine may be habit-forming and should be used only by the person it was prescribed for. Keep track of how many pills have been used from each new bottle of this medicine. Phentermine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

You may have withdrawal symptoms, such as depression and extreme tiredness, when you stop using phentermine after a long period of use. Do not stop using phentermine suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

What should I discuss with my healthcare provider before taking Zantryl (phentermine)?

Do not take phentermine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take phentermine before the MAO inhibitor has cleared from your body.

Taking phentermine together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take phentermine with any other diet medications without your doctor’s advice.

Do not take this medication if you are allergic to phentermine or other stimulants, or if you have:

heart disease or high blood pressure;

arteriosclerosis (hardening of the arteries);

an overactive thyroid;

glaucoma;

if you are in an agitated state; or

if you have a history of drug or alcohol abuse.

Before taking phentermine, tell your doctor if you are allergic to any drugs, or if you have:

a thyroid disorder;

anxiety disorder;

diabetes; or

epilepsy or another seizure disorder.

If you have any of these conditions, you may need a dose adjustment or special tests during treatment.

It is not known whether phentermine will harm an unborn baby. Do not take phentermine without telling your doctor if you are pregnant. It is also not known whether phentermine passes into breast milk or if it could harm a nursing baby. Do not take phentermine without telling your doctor if you are breast-feeding a baby. Do not give this medication to anyone younger than 16 years old without the advice of a doctor. Phentermine may be habit-forming and should be used only by the person it was prescribed for. Phentermine should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

How should I take Zantryl (phentermine)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

It is best to take phentermine on an empty stomach before breakfast, or at least 10 to 14 hours before bedtime. Do not take more phentermine for an increased effect. Taking too much of this medication can cause serious, life-threatening side effects. Do not crush, chew, break, or open an extended-release capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.

Phentermine should be taken only for a short time, such as a few weeks.

Taking high doses of phentermine over long periods of time can cause severe skin problems, sleep problems (insomnia), personality changes, and feeling hyperactive or irritable.

Stop taking phentermine if you have increased hunger or if you otherwise think the medication is not working properly.

You may have withdrawal symptoms when you stop using phentermine after a long period of use. Do not stop using the medication suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

Do not take phentermine in the evening because it may cause sleep problems (insomnia).

Store this medication at room temperature away from moisture and heat. Keep track of how many pills have been used from each new bottle of this medicine. Phentermine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medication. An overdose of phentermine can be fatal.

Overdose symptoms may include confusion, hallucinations, feeling restless or aggressive, nausea, vomiting, diarrhea, stomach pain, irregular heartbeat, tremors, rapid breathing, confusion, hallucinations, feeling light-headed, fainting, or seizure (convulsions).

What should I avoid while taking Zantryl (phentermine)?

Avoid drinking alcohol. It can increase some of the side effects of phentermine. Phentermine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Zantryl (phentermine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using phentermine and call your doctor at once if you have any of these serious side effects:

feeling short of breath, even with mild exertion;

swelling, rapid weight gain;

chest pain, fast or uneven heartbeat, feeling like you might pass out;

unusual thoughts or behavior, feeling restless or confused; or

dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

feeling nervous or anxious;

headache, dizziness, tremors;

trouble sleeping (insomnia);

dry mouth or an unpleasant taste in your mouth;

diarrhea or constipation; or

itching.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Zantryl (phentermine)?

Before taking phentermine, tell your doctor if you are using any of the following drugs:

medicines to treat high blood pressure;

insulin or diabetes medication you take by mouth;

guanadrel (Hylorel), guanethidine (Ismelin);

antidepressants such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft); or

antidepressants such as amitriptyline (Elavil, Etrafon), amoxapine (Ascendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil).

This list is not complete and there may be other drugs that can interact with phentermine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Westrim LA

Westrim LA

Generic Name: phenylpropanolamine (fen ill proe pa NOLE a meen)

What is Westrim LA (phenylpropanolamine)?

Phenylpropanolamine is a decongestant. It works by constricting (shrinking) blood vessels (veins and arteries) in your body. Constriction of blood vessels in your sinuses, nose, and chest allows drainage of those areas, which decreases congestion.

Phenylpropanolamine is used to treat the congestion associated with allergies, hay fever, sinus irritation, and the common cold. Phenylpropanolamine also causes a decrease in appetite and is used in some over-the-counter diet aids.

Phenylpropanolamine has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.

Phenylpropanolamine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Westrim LA (phenylpropanolamine)?

Phenylpropanolamine has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.

Do not take phenylpropanolamine for longer than 7 days if your condition does not improve or if your symptoms are accompanied by a high fever.

Do not take more of this medication than is recommended on the package or by your doctor. Use caution when driving, operating machinery, or performing other hazardous activities. Phenylpropanolamine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Who should not take Westrim LA (phenylpropanolamine)?

Do not take phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

high blood pressure;

any type of heart disease, hardening of the arteries, or irregular heartbeat;

thyroid problems;

diabetes;

glaucoma or increased pressure in your eye;

an enlarged prostate or difficulty urinating; or

liver or kidney disease.

You may not be able to take phenylpropanolamine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

It is not known whether phenylpropanolamine will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. Infants are especially sensitive to the effects of phenylpropanolamine. Do not take this drug if you are breast-feeding a baby. If you are over 60 years of age, you may be more likely to experience side effects from phenylpropanolamine. You may require a lower dose of this medication. Using a short-acting formulation of phenylpropanolamine (not a long-acting or a controlled-release formulation) may be safer if you are over 60 years of age.

How should I take Westrim LA (phenylpropanolamine)?

Take phenylpropanolamine exactly as directed by your doctor, or follow the instructions that accompany the package. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Never take this medication in larger doses or more often than is recommended. Too much phenylpropanolamine could be very harmful.

If your symptoms are accompanied by a high fever, or if they do not improve in 7 days, see your doctor.

Store phenylpropanolamine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a phenylpropanolamine overdose include extreme tiredness, sweating, dizziness, a slow heart beat, and a coma.

What should I avoid while taking Westrim LA (phenylpropanolamine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Phenylpropanolamine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Never take this medication in larger doses or more often than is recommended. Too much phenylpropanolamine could be very harmful.

Westrim LA (phenylpropanolamine) side effects

If you experience any of the following serious side effects from this medication, stop taking phenylpropanolamine and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

seizures;

unusual behavior or hallucinations; or

an irregular or fast heartbeat.

Other, less serious side effects may be more likely to occur. Continue to take phenylpropanolamine and talk to your doctor if you experience

dizziness, lightheadedness, or drowsiness;

headache;

insomnia;

anxiety;

tremor (shaking) or restlessness;

nausea or vomiting; or

sweating.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Westrim LA (phenylpropanolamine)?

Do not take phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Phenylpropanolamine may also interact with the following medicines:

furazolidone (Furoxone);

guanethidine (Ismelin);

indomethacin (Indocin);

methyldopa (Aldomet);

bromocriptine (Parlodel);

caffeine in cola, tea, coffee, chocolate, and other products;

theophylline (Theo-Dur, Theochron, Theolair, others);

Drugs other than those listed here may also interact with phenylpropanolamine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Westrim

Westrim

Generic Name: phenylpropanolamine (fen ill proe pa NOLE a meen)

What is Westrim (phenylpropanolamine)?

Phenylpropanolamine is a decongestant. It works by constricting (shrinking) blood vessels (veins and arteries) in your body. Constriction of blood vessels in your sinuses, nose, and chest allows drainage of those areas, which decreases congestion.

Phenylpropanolamine is used to treat the congestion associated with allergies, hay fever, sinus irritation, and the common cold. Phenylpropanolamine also causes a decrease in appetite and is used in some over-the-counter diet aids.

Phenylpropanolamine has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.

Phenylpropanolamine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Westrim (phenylpropanolamine)?

Phenylpropanolamine has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.

Do not take phenylpropanolamine for longer than 7 days if your condition does not improve or if your symptoms are accompanied by a high fever.

Do not take more of this medication than is recommended on the package or by your doctor. Use caution when driving, operating machinery, or performing other hazardous activities. Phenylpropanolamine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Who should not take Westrim (phenylpropanolamine)?

Do not take phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

high blood pressure;

any type of heart disease, hardening of the arteries, or irregular heartbeat;

thyroid problems;

diabetes;

glaucoma or increased pressure in your eye;

an enlarged prostate or difficulty urinating; or

liver or kidney disease.

You may not be able to take phenylpropanolamine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

It is not known whether phenylpropanolamine will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. Infants are especially sensitive to the effects of phenylpropanolamine. Do not take this drug if you are breast-feeding a baby. If you are over 60 years of age, you may be more likely to experience side effects from phenylpropanolamine. You may require a lower dose of this medication. Using a short-acting formulation of phenylpropanolamine (not a long-acting or a controlled-release formulation) may be safer if you are over 60 years of age.

How should I take Westrim (phenylpropanolamine)?

Take phenylpropanolamine exactly as directed by your doctor, or follow the instructions that accompany the package. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Never take this medication in larger doses or more often than is recommended. Too much phenylpropanolamine could be very harmful.

If your symptoms are accompanied by a high fever, or if they do not improve in 7 days, see your doctor.

Store phenylpropanolamine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a phenylpropanolamine overdose include extreme tiredness, sweating, dizziness, a slow heart beat, and a coma.

What should I avoid while taking Westrim (phenylpropanolamine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Phenylpropanolamine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Never take this medication in larger doses or more often than is recommended. Too much phenylpropanolamine could be very harmful.

Westrim (phenylpropanolamine) side effects

If you experience any of the following serious side effects from this medication, stop taking phenylpropanolamine and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

seizures;

unusual behavior or hallucinations; or

an irregular or fast heartbeat.

Other, less serious side effects may be more likely to occur. Continue to take phenylpropanolamine and talk to your doctor if you experience

dizziness, lightheadedness, or drowsiness;

headache;

insomnia;

anxiety;

tremor (shaking) or restlessness;

nausea or vomiting; or

sweating.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Westrim (phenylpropanolamine)?

Do not take phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Phenylpropanolamine may also interact with the following medicines:

furazolidone (Furoxone);

guanethidine (Ismelin);

indomethacin (Indocin);

methyldopa (Aldomet);

bromocriptine (Parlodel);

caffeine in cola, tea, coffee, chocolate, and other products;

theophylline (Theo-Dur, Theochron, Theolair, others);

Drugs other than those listed here may also interact with phenylpropanolamine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Teramine

Teramine

Generic Name: phentermine (FEN ter meen)

What is Teramine (phentermine)?

Phentermine is a stimulant that is similar to an amphetamine. Phentermine is an appetite suppressant that affects the central nervous system.

Phentermine is used togther with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes.

Phentermine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Teramine (phentermine)?

Taking phentermine together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take phentermine with any other diet medications without your doctor’s advice.

Phentermine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of phentermine. Phentermine may be habit-forming and should be used only by the person it was prescribed for. Keep track of how many pills have been used from each new bottle of this medicine. Phentermine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

You may have withdrawal symptoms, such as depression and extreme tiredness, when you stop using phentermine after a long period of use. Do not stop using phentermine suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

What should I discuss with my healthcare provider before taking Teramine (phentermine)?

Do not take phentermine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take phentermine before the MAO inhibitor has cleared from your body.

Taking phentermine together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take phentermine with any other diet medications without your doctor’s advice.

Do not take this medication if you are allergic to phentermine or other stimulants, or if you have:

heart disease or high blood pressure;

arteriosclerosis (hardening of the arteries);

an overactive thyroid;

glaucoma;

if you are in an agitated state; or

if you have a history of drug or alcohol abuse.

Before taking phentermine, tell your doctor if you are allergic to any drugs, or if you have:

a thyroid disorder;

anxiety disorder;

diabetes; or

epilepsy or another seizure disorder.

If you have any of these conditions, you may need a dose adjustment or special tests during treatment.

It is not known whether phentermine will harm an unborn baby. Do not take phentermine without telling your doctor if you are pregnant. It is also not known whether phentermine passes into breast milk or if it could harm a nursing baby. Do not take phentermine without telling your doctor if you are breast-feeding a baby. Do not give this medication to anyone younger than 16 years old without the advice of a doctor. Phentermine may be habit-forming and should be used only by the person it was prescribed for. Phentermine should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

How should I take Teramine (phentermine)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

It is best to take phentermine on an empty stomach before breakfast, or at least 10 to 14 hours before bedtime. Do not take more phentermine for an increased effect. Taking too much of this medication can cause serious, life-threatening side effects. Do not crush, chew, break, or open an extended-release capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.

Phentermine should be taken only for a short time, such as a few weeks.

Taking high doses of phentermine over long periods of time can cause severe skin problems, sleep problems (insomnia), personality changes, and feeling hyperactive or irritable.

Stop taking phentermine if you have increased hunger or if you otherwise think the medication is not working properly.

You may have withdrawal symptoms when you stop using phentermine after a long period of use. Do not stop using the medication suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

Do not take phentermine in the evening because it may cause sleep problems (insomnia).

Store this medication at room temperature away from moisture and heat. Keep track of how many pills have been used from each new bottle of this medicine. Phentermine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medication. An overdose of phentermine can be fatal.

Overdose symptoms may include confusion, hallucinations, feeling restless or aggressive, nausea, vomiting, diarrhea, stomach pain, irregular heartbeat, tremors, rapid breathing, confusion, hallucinations, feeling light-headed, fainting, or seizure (convulsions).

What should I avoid while taking Teramine (phentermine)?

Avoid drinking alcohol. It can increase some of the side effects of phentermine. Phentermine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Teramine (phentermine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using phentermine and call your doctor at once if you have any of these serious side effects:

feeling short of breath, even with mild exertion;

swelling, rapid weight gain;

chest pain, fast or uneven heartbeat, feeling like you might pass out;

unusual thoughts or behavior, feeling restless or confused; or

dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

feeling nervous or anxious;

headache, dizziness, tremors;

trouble sleeping (insomnia);

dry mouth or an unpleasant taste in your mouth;

diarrhea or constipation; or

itching.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Teramine (phentermine)?

Before taking phentermine, tell your doctor if you are using any of the following drugs:

medicines to treat high blood pressure;

insulin or diabetes medication you take by mouth;

guanadrel (Hylorel), guanethidine (Ismelin);

antidepressants such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft); or

antidepressants such as amitriptyline (Elavil, Etrafon), amoxapine (Ascendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil).

This list is not complete and there may be other drugs that can interact with phentermine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Statobex

Statobex

Generic Name: phendimetrazine (fen di MEH tra zeen)

What is Statobex (phendimetrazine)?

Phendimetrazine is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an “anorectic” or “anorexigenic” drug. Phendimetrazine stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.

Phendimetrazine is used as a short-term supplement to diet and exercise in the treatment of obesity.

Phendimetrazine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Statobex (phendimetrazine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Phendimetrazine may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities. Phendimetrazine is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually. Do not crush, chew, or open any “once-daily” phendimetrazine tablets or capsules. Swallow them whole.

What should I discuss with my healthcare provider before taking Statobex (phendimetrazine)?

You cannot take phendimetrazine if you

have heart disease or high blood pressure;

have arteriosclerosis (hardening of the arteries);

have glaucoma;

have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days; or

have a history of drug or alcohol abuse.

Before taking this medication, tell your doctor if you have

problems with your thyroid,

an anxiety disorder,

epilepsy or another seizure disorder, or

diabetes.

You may not be able to take phendimetrazine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

It is not known whether phendimetrazine will harm an unborn baby. Do not take phendimetrazine without first talking to your doctor if you are pregnant. It is also not known whether phendimetrazine passes into breast milk. Do not take phendimetrazine without first talking to your doctor if you are breast-feeding a baby.

How should I take Statobex (phendimetrazine)?

Take phendimetrazine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Phendimetrazine is usually taken once a day (sustained release formula) or two to three times daily (immediate-release formula) before meals on an empty stomach.

Do not take phendimetrazine in the evening because it may cause insomnia.

Do not crush, chew, or open any “once-daily” phendimetrazine tablets or capsules. Swallow them whole. Never take more of this medication than is prescribed for you. Too much phendimetrazine could be very dangerous to your health. Store phendimetrazine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose or if it is already evening, skip the missed dose and take only your next regularly scheduled dose. A dose taken too late in the day will cause insomnia. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a phendimetrazine overdose include restlessness, tremor, rapid breathing, confusion, hallucinations, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures.

What should I avoid while taking Statobex (phendimetrazine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Phendimetrazine may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities.

Do not take phendimetrazine late in the day. A dose taken too late in the day can cause insomnia.

Statobex (phendimetrazine) side effects

If you experience any of the following serious side effects, stop taking phendimetrazine and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

an irregular heartbeat or very high blood pressure (severe headache, blurred vision); or

hallucinations, abnormal behavior, or confusion.

Other, less serious side effects may be more likely to occur. Continue to take phendimetrazine and talk to your doctor if you experience

restlessness or tremor,

nervousness or anxiety,

headache or dizziness,

insomnia,

dry mouth or an unpleasant taste in your mouth,

diarrhea or constipation, or

impotence or changes in your sex drive.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Statobex (phendimetrazine)?

You cannot take phendimetrazine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days.

Changes in insulin and other diabetes drug therapies may be necessary during treatment with phendimetrazine.

Phendimetrazine may reduce the effects of guanethidine (Ismelin). This could lead to an increase in blood pressure. Tell your doctor if you are taking guanethidine.

Before taking this medication, tell your doctor if you are taking a tricyclic antidepressant such as amitriptyline (Elavil), amoxapine (Asendin), doxepin (Sinequan), nortriptyline (Pamelor), imipramine (Tofranil), clomipramine (Anafranil), protriptyline (Vivactil), or desipramine (Norpramin). These drugs may decrease the effects of phendimetrazine.

Drugs other than those listed here may also interact with phendimetrazine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

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