Archive for the ‘peripheral vasodilators’ Category

Voxsuprine

Voxsuprine

Generic Name: isoxsuprine (eye SOCK soo prin)

What is Voxsuprine (isoxsuprine)?

Isoxsuprine is in a class of drugs called vasodilators. Isoxsuprine relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.

These actions may help treat the symptoms of conditions such as cerebral vascular insufficiency (poor blood flow to the brain), arteriosclerosis (hardening of the arteries), Raynaud’s phenomenon, and other conditions involving poor blood flow in the veins and arteries.

Isoxsuprine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Voxsuprine (isoxsuprine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Isoxuprine may cause dizziness. If you experience dizziness, avoid these activities. Also, rise slowly from a sitting or lying position to avoid falling.

Notify your doctor if you experience a rash or bothersome irregular heartbeats.

Isoxsuprine has been withdrawn from the U.S. market.

What should I discuss with my healthcare provider before taking Voxsuprine (isoxsuprine)?

Isoxsuprine should not be used immediately postpartum (after delivering a baby), or if you have a bleeding disorder. Talk to your doctor about any other medical conditions that you have.

Isoxsuprine is in the FDA pregnancy category C. This means that it is not known whether isoxsuprine will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether isoxsuprine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take Voxsuprine (isoxsuprine)?

Take isoxsuprine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Isoxsuprine is usually taken three or four times a day. Follow your doctor’s instructions.

It is important to take isoxsuprine regularly to get the most benefit.

Your doctor may want you to have blood tests or other medical evaluations during treatment with isoxsuprine to monitor progress and side effects.

Store isoxsuprine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of an isoxsuprine overdose include weakness, lightheadedness, fainting, nausea, and vomiting.

What should I avoid while taking Voxsuprine (isoxsuprine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Isoxsuprine may cause dizziness. If you experience dizziness, avoid these activities. Also, rise slowly from a sitting or lying position to avoid falling.

Voxsuprine (isoxsuprine) side effects

Stop taking isoxsuprine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).

Stop taking isoxsuprine and contact your doctor if you develop a rash.

Other, less serious side effects may be more likely to occur. Continue to take isoxsuprine and talk to your doctor if you experience

chest pain or an irregular heartbeat (call your doctor if this becomes bothersome);

nausea or vomiting; or

dizziness or weakness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Voxsuprine (isoxsuprine)?

Drugs used to treat high blood pressure and other heart conditions may increase the effects of isoxsuprine. Special monitoring may be necessary.

Drugs other than those listed here may also interact with isoxsuprine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Vasodilan

Vasodilan

Vasodilan is used for:

Improving blood flow in some conditions (eg, cerebral vascular insufficiency, arteriosclerosis obliterans, Buerger disease, Raynaud disease). It may also be used for other conditions as determined by your doctor.

Vasodilan is a vasodilating agent. It works by relaxing and widening the blood vessels in muscles and other tissues, which helps to improve blood flow (circulation) in these muscles and tissues.

Do NOT use Vasodilan if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Vasodilan :

Some medical conditions may interact with Vasodilan . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Vasodilan . However, no specific interactions with Vasodilan are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Vasodilan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Vasodilan :

Use Vasodilan as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Vasodilan .

Important safety information:

Possible side effects of Vasodilan :

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fast or irregular heartbeat; severe or persistent dizziness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Store Vasodilan at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Vasodilan out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Vasodilan . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Vasodilan resources

Compare Vasodilan with other medications for the treatment of:

Pavagen

Pavagen

Generic Name: papaverine (pa PAV uh reen)

What is Pavagen (papaverine)?

Papaverine is in a class of drugs called vasodilators. Papaverine relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily. These actions may help to increase the amount of oxygen-rich blood in your brain, heart, and muscles.

Papaverine may also be useful in treating conditions involving spasms of the intestines and urinary tract.

Papaverine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Pavagen (papaverine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Papaverine may cause dizziness. If you experience dizziness, avoid these activities. If you experience dizziness, rise slowly from a sitting or lying position to avoid falling. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking papaverine.

Notify your doctor if you experience especially bothersome sweating, rash, flushing, headache, tiredness, yellowing of your skin, nausea, decreased appetite, diarrhea, or constipation.

Who should not take Pavagen (papaverine)?

Before taking this medication, tell your doctor if you have

heart disease or irregular heartbeats,

liver disease,

glaucoma, or

Parkinson’s disease.

You may not be able to take papaverine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Papaverine is in the FDA pregnancy category C. This means that it is not known whether papaverine will harm an unborn baby. Do not take papaverine without first talking to your doctor if you are pregnant. It is not known whether papaverine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take Pavagen (papaverine)?

Take papaverine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. The regular-release form of papaverine is usually taken three to five times a day. The timed-release tablets and capsules are usually taken two or three times a day (every 8 to 12 hours). Follow your doctor’s instructions. Do not crush, chew, break, or open the timed-release tablets or capsules. Swallow them whole. They are specially formulated to release slowly in your body. Store papaverine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a papaverine overdose include drowsiness, weakness, double vision, poor coordination, headache, blue-colored lips or skin, and coma.

What should I avoid while taking Pavagen (papaverine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Papaverine may cause dizziness. If you experience dizziness, avoid these activities. If you experience dizziness, rise slowly from a sitting or lying position to avoid falling. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking papaverine. Do not crush, chew, break, or open the timed-release tablets or capsules. Swallow them whole. These are specially formulated to release slowly in your body.

Pavagen (papaverine) side effects

Stop taking papaverine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Stop taking papaverine and contact your doctor if your skin or eyes develop a yellow tint.

Other, less serious side effects may be more likely to occur. Continue to take papaverine and talk to your doctor if you experience

nausea, decreased appetite, diarrhea, or constipation;

dizziness or drowsiness;

headache;

sweating and flushing;

a rash; or

irregular heartbeats.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Pavagen (papaverine)?

Papaverine may decrease the effects of levodopa (Dopar, Larodopa) which is used to treat Parkinson’s disease. You may need a change in your levodopa dosage if you are taking levodopa.

Drugs other than those listed here may also interact with papaverine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Pavacot

Pavacot

Generic Name: papaverine (pa PAV uh reen)

What is Pavacot (papaverine)?

Papaverine is in a class of drugs called vasodilators. Papaverine relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily. These actions may help to increase the amount of oxygen-rich blood in your brain, heart, and muscles.

Papaverine may also be useful in treating conditions involving spasms of the intestines and urinary tract.

Papaverine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Pavacot (papaverine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Papaverine may cause dizziness. If you experience dizziness, avoid these activities. If you experience dizziness, rise slowly from a sitting or lying position to avoid falling. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking papaverine.

Notify your doctor if you experience especially bothersome sweating, rash, flushing, headache, tiredness, yellowing of your skin, nausea, decreased appetite, diarrhea, or constipation.

Who should not take Pavacot (papaverine)?

Before taking this medication, tell your doctor if you have

heart disease or irregular heartbeats,

liver disease,

glaucoma, or

Parkinson’s disease.

You may not be able to take papaverine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Papaverine is in the FDA pregnancy category C. This means that it is not known whether papaverine will harm an unborn baby. Do not take papaverine without first talking to your doctor if you are pregnant. It is not known whether papaverine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take Pavacot (papaverine)?

Take papaverine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. The regular-release form of papaverine is usually taken three to five times a day. The timed-release tablets and capsules are usually taken two or three times a day (every 8 to 12 hours). Follow your doctor’s instructions. Do not crush, chew, break, or open the timed-release tablets or capsules. Swallow them whole. They are specially formulated to release slowly in your body. Store papaverine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a papaverine overdose include drowsiness, weakness, double vision, poor coordination, headache, blue-colored lips or skin, and coma.

What should I avoid while taking Pavacot (papaverine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Papaverine may cause dizziness. If you experience dizziness, avoid these activities. If you experience dizziness, rise slowly from a sitting or lying position to avoid falling. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking papaverine. Do not crush, chew, break, or open the timed-release tablets or capsules. Swallow them whole. These are specially formulated to release slowly in your body.

Pavacot (papaverine) side effects

Stop taking papaverine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Stop taking papaverine and contact your doctor if your skin or eyes develop a yellow tint.

Other, less serious side effects may be more likely to occur. Continue to take papaverine and talk to your doctor if you experience

nausea, decreased appetite, diarrhea, or constipation;

dizziness or drowsiness;

headache;

sweating and flushing;

a rash; or

irregular heartbeats.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Pavacot (papaverine)?

Papaverine may decrease the effects of levodopa (Dopar, Larodopa) which is used to treat Parkinson’s disease. You may need a change in your levodopa dosage if you are taking levodopa.

Drugs other than those listed here may also interact with papaverine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Pavabid Plateau

Pavabid Plateau

Generic Name: papaverine (pa PAV uh reen)

What is Pavabid Plateau (papaverine)?

Papaverine is in a class of drugs called vasodilators. Papaverine relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily. These actions may help to increase the amount of oxygen-rich blood in your brain, heart, and muscles.

Papaverine may also be useful in treating conditions involving spasms of the intestines and urinary tract.

Papaverine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Pavabid Plateau (papaverine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Papaverine may cause dizziness. If you experience dizziness, avoid these activities. If you experience dizziness, rise slowly from a sitting or lying position to avoid falling. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking papaverine.

Notify your doctor if you experience especially bothersome sweating, rash, flushing, headache, tiredness, yellowing of your skin, nausea, decreased appetite, diarrhea, or constipation.

Who should not take Pavabid Plateau (papaverine)?

Before taking this medication, tell your doctor if you have

heart disease or irregular heartbeats,

liver disease,

glaucoma, or

Parkinson’s disease.

You may not be able to take papaverine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Papaverine is in the FDA pregnancy category C. This means that it is not known whether papaverine will harm an unborn baby. Do not take papaverine without first talking to your doctor if you are pregnant. It is not known whether papaverine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take Pavabid Plateau (papaverine)?

Take papaverine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. The regular-release form of papaverine is usually taken three to five times a day. The timed-release tablets and capsules are usually taken two or three times a day (every 8 to 12 hours). Follow your doctor’s instructions. Do not crush, chew, break, or open the timed-release tablets or capsules. Swallow them whole. They are specially formulated to release slowly in your body. Store papaverine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a papaverine overdose include drowsiness, weakness, double vision, poor coordination, headache, blue-colored lips or skin, and coma.

What should I avoid while taking Pavabid Plateau (papaverine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Papaverine may cause dizziness. If you experience dizziness, avoid these activities. If you experience dizziness, rise slowly from a sitting or lying position to avoid falling. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking papaverine. Do not crush, chew, break, or open the timed-release tablets or capsules. Swallow them whole. These are specially formulated to release slowly in your body.

Pavabid Plateau (papaverine) side effects

Stop taking papaverine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Stop taking papaverine and contact your doctor if your skin or eyes develop a yellow tint.

Other, less serious side effects may be more likely to occur. Continue to take papaverine and talk to your doctor if you experience

nausea, decreased appetite, diarrhea, or constipation;

dizziness or drowsiness;

headache;

sweating and flushing;

a rash; or

irregular heartbeats.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Pavabid Plateau (papaverine)?

Papaverine may decrease the effects of levodopa (Dopar, Larodopa) which is used to treat Parkinson’s disease. You may need a change in your levodopa dosage if you are taking levodopa.

Drugs other than those listed here may also interact with papaverine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Para-Time S. R.

Para-Time S. R.

Generic Name: papaverine (pa PAV uh reen)

What is Para-Time S. R. (papaverine)?

Papaverine is in a class of drugs called vasodilators. Papaverine relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily. These actions may help to increase the amount of oxygen-rich blood in your brain, heart, and muscles.

Papaverine may also be useful in treating conditions involving spasms of the intestines and urinary tract.

Papaverine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Para-Time S. R. (papaverine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Papaverine may cause dizziness. If you experience dizziness, avoid these activities. If you experience dizziness, rise slowly from a sitting or lying position to avoid falling. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking papaverine.

Notify your doctor if you experience especially bothersome sweating, rash, flushing, headache, tiredness, yellowing of your skin, nausea, decreased appetite, diarrhea, or constipation.

Who should not take Para-Time S. R. (papaverine)?

Before taking this medication, tell your doctor if you have

heart disease or irregular heartbeats,

liver disease,

glaucoma, or

Parkinson’s disease.

You may not be able to take papaverine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Papaverine is in the FDA pregnancy category C. This means that it is not known whether papaverine will harm an unborn baby. Do not take papaverine without first talking to your doctor if you are pregnant. It is not known whether papaverine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take Para-Time S. R. (papaverine)?

Take papaverine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. The regular-release form of papaverine is usually taken three to five times a day. The timed-release tablets and capsules are usually taken two or three times a day (every 8 to 12 hours). Follow your doctor’s instructions. Do not crush, chew, break, or open the timed-release tablets or capsules. Swallow them whole. They are specially formulated to release slowly in your body. Store papaverine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a papaverine overdose include drowsiness, weakness, double vision, poor coordination, headache, blue-colored lips or skin, and coma.

What should I avoid while taking Para-Time S. R. (papaverine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Papaverine may cause dizziness. If you experience dizziness, avoid these activities. If you experience dizziness, rise slowly from a sitting or lying position to avoid falling. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking papaverine. Do not crush, chew, break, or open the timed-release tablets or capsules. Swallow them whole. These are specially formulated to release slowly in your body.

Para-Time S. R. (papaverine) side effects

Stop taking papaverine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Stop taking papaverine and contact your doctor if your skin or eyes develop a yellow tint.

Other, less serious side effects may be more likely to occur. Continue to take papaverine and talk to your doctor if you experience

nausea, decreased appetite, diarrhea, or constipation;

dizziness or drowsiness;

headache;

sweating and flushing;

a rash; or

irregular heartbeats.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Para-Time S. R. (papaverine)?

Papaverine may decrease the effects of levodopa (Dopar, Larodopa) which is used to treat Parkinson’s disease. You may need a change in your levodopa dosage if you are taking levodopa.

Drugs other than those listed here may also interact with papaverine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Papacon

Papacon

Generic Name: papaverine (pa PAV uh reen)

What is Papacon (papaverine)?

Papaverine is in a class of drugs called vasodilators. Papaverine relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily. These actions may help to increase the amount of oxygen-rich blood in your brain, heart, and muscles.

Papaverine may also be useful in treating conditions involving spasms of the intestines and urinary tract.

Papaverine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Papacon (papaverine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Papaverine may cause dizziness. If you experience dizziness, avoid these activities. If you experience dizziness, rise slowly from a sitting or lying position to avoid falling. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking papaverine.

Notify your doctor if you experience especially bothersome sweating, rash, flushing, headache, tiredness, yellowing of your skin, nausea, decreased appetite, diarrhea, or constipation.

Who should not take Papacon (papaverine)?

Before taking this medication, tell your doctor if you have

heart disease or irregular heartbeats,

liver disease,

glaucoma, or

Parkinson’s disease.

You may not be able to take papaverine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Papaverine is in the FDA pregnancy category C. This means that it is not known whether papaverine will harm an unborn baby. Do not take papaverine without first talking to your doctor if you are pregnant. It is not known whether papaverine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take Papacon (papaverine)?

Take papaverine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. The regular-release form of papaverine is usually taken three to five times a day. The timed-release tablets and capsules are usually taken two or three times a day (every 8 to 12 hours). Follow your doctor’s instructions. Do not crush, chew, break, or open the timed-release tablets or capsules. Swallow them whole. They are specially formulated to release slowly in your body. Store papaverine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a papaverine overdose include drowsiness, weakness, double vision, poor coordination, headache, blue-colored lips or skin, and coma.

What should I avoid while taking Papacon (papaverine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Papaverine may cause dizziness. If you experience dizziness, avoid these activities. If you experience dizziness, rise slowly from a sitting or lying position to avoid falling. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking papaverine. Do not crush, chew, break, or open the timed-release tablets or capsules. Swallow them whole. These are specially formulated to release slowly in your body.

Papacon (papaverine) side effects

Stop taking papaverine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Stop taking papaverine and contact your doctor if your skin or eyes develop a yellow tint.

Other, less serious side effects may be more likely to occur. Continue to take papaverine and talk to your doctor if you experience

nausea, decreased appetite, diarrhea, or constipation;

dizziness or drowsiness;

headache;

sweating and flushing;

a rash; or

irregular heartbeats.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Papacon (papaverine)?

Papaverine may decrease the effects of levodopa (Dopar, Larodopa) which is used to treat Parkinson’s disease. You may need a change in your levodopa dosage if you are taking levodopa.

Drugs other than those listed here may also interact with papaverine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Cyclospasmol

Cyclospasmol

Generic Name: cyclandelate (sye KLAN de late)

What is Cyclospasmol (cyclandelate)?

Cyclandelate is in a class of drugs called vasodilators. Cyclandelate relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.

These actions may help treat the symptoms of conditions such as leg cramps, arteriosclerosis (hardening of the arteries), Raynaud’s phenomenon, and other conditions that involve poor blood flow in your veins and arteries.

Cyclandelate is not commercially available in the United States.

Cyclandelate may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Cyclospasmol (cyclandelate)?

Cyclandelate is not commercially available in the United States.

Take cyclandelate with food or an antacid to lessen stomach discomfort.

What should I discuss with my healthcare provider before taking Cyclospasmol (cyclandelate)?

Before taking this medication, tell your doctor if you have

serious coronary artery disease;

peripheral or cerebral vascular disease;

glaucoma, or

bleeding or blood problems.

How should I take Cyclospasmol (cyclandelate)?

Take cyclandelate exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Take cyclandelate with food or an antacid to lessen stomach discomfort. Cyclandelate is usually taken two to four times a day, before meals and at bedtime. Follow your doctor’s instructions. Store cyclandelate at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a cyclandelate overdose include lightheadedness, weakness, fainting, headache, and a faint heartbeat.

What should I avoid while taking Cyclospasmol (cyclandelate)?

There are no restrictions on foods, beverages, or activities during therapy with cyclandelate. Follow any special instructions you receive from your doctor.

Cyclospasmol (cyclandelate) side effects

Stop taking cyclandelate and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take cyclandelate and talk to your doctor if you experience

heartburn, stomach upset, or belching;

flushing;

headache;

a fast heartbeat; or

weakness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Cyclospasmol (cyclandelate)?

Drugs used to treat high blood pressure and other heart conditions may increase the effects of cyclandelate. Special monitoring may be necessary.

Drugs other than those listed here may also interact with cyclandelate or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

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