Archive for the ‘prolactin inhibitors’ Category

Cycloset

Cycloset

Generic Name: bromocriptine mesylate

FDA Approves Cycloset

The U.S. Food and Drug Administration (FDA) has approved Cycloset (bromocriptine mesylate) for the treatment of Type 2 diabetes. Cycloset improves glycemic control across a broad patient population as a monotherapy or as an adjunctive therapy to sulfonylurea, metformin plus sulfonylurea, and single or dual oral hypoglycaemic agent therapies.

Cycloset is the first drug to be approved subsequent to the FDA’s new guidelines that require studies demonstrating that diabetes drugs do not increase cardiovascular risk. A 52 week, double-blind safety trial of 3,000 patients treated with Cycloset did not show an increase in pre-specified and independently adjudicated adverse cardiovascular outcomes?

Parlodel

Parlodel

Parlodel is used for:

Treating Parkinson disease, certain conditions caused by too much prolactin in the blood (eg, excessive or abnormal breast milk production), certain menstrual problems, or abnormally large growth of certain body parts (acromegaly). It may also be used for other conditions as determined by your doctor.

Parlodel is a dopamine agonist. It works by blocking the release of prolactin from the pituitary gland and lowering growth hormone levels (in patients with acromegaly). In Parkinson disease, Parlodel works by stimulating dopamine receptors in certain parts of the brain.

Do NOT use Parlodel if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Parlodel :

Some medical conditions may interact with Parlodel . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Parlodel . Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Parlodel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Parlodel :

Use Parlodel as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Parlodel .

Important safety information:

Possible side effects of Parlodel :

All medicines may cause side effects, but many people have no, or minor, side effects.

Cold sensitivity in fingers and toes; constipation; diarrhea; dizziness; drowsiness; dry mouth; fatigue; headache; indigestion; lightheadedness; loss of appetite; nausea; stomach cramps; stuffy nose; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal involuntary movements; bloody or black, tarry stools; chest pain; depression; fainting; hallucinations; one-sided weakness; persistent, watery nasal discharge; progressive, severe headache; shortness of breath; ringing in the ears; seizures; slurred speech or trouble speaking; stomach pain; sudden confusion; sudden daytime sleepiness; sudden loss of coordination; vision changes; vomiting blood or a substance like coffee grounds.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Store Parlodel between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Parlodel out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Parlodel . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Parlodel resources

Compare Parlodel with other medications for the treatment of:

Dostinex

Dostinex

Dostinex is used for:

Treating disorders associated with high levels of the hormone prolactin, either due to tumors in the pituitary gland or to unknown causes. It may also be used for other conditions as determined by your doctor.

Dostinex is a dopamine receptor agonist. It works by blocking prolactin secretion from the pituitary gland.

Do NOT use Dostinex if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Dostinex :

Some medical conditions may interact with Dostinex . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Dostinex . Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dostinex may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Dostinex :

Use Dostinex as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Dostinex .

Important safety information:

Possible side effects of Dostinex :

All medicines may cause side effects, but many people have no, or minor, side effects.

Constipation; dizziness; headache; indigestion; nausea; tiredness or weakness; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); behavior changes (eg, aggression, increased gambling or sexual urges); chest pain; confusion; cough; depression; fainting; hallucinations; irregular heartbeat; mood or mental changes; shortness of breath; sudden unexplained weight gain; swelling of hands or feet; vision disturbances.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Store Dostinex at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dostinex out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Dostinex . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Dostinex resources

Compare Dostinex with other medications for the treatment of:

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