Archive for the ‘antihyperuricemic agents’ Category

Elitek

Elitek

Elitek can cause a severe allergic reaction. If you develop new symptoms such as chest pain, trouble breathing, severe dizziness, a rash, or hives, stop using Elitek and seek immediate medical attention. Do not restart Elitek if a severe allergic reaction has occurred. Consult your doctor or pharmacist for more details.

Do not take Elitek if you have a metabolic condition called glucose-6-phosphate dehydrogenase (G6PD) deficiency because it can severely damage your red blood cells, leading to anemia (hemolysis). If you are of African or Mediterranean descent, you may be at higher risk for G6PD deficiency and should be tested to see if you have this condition before starting Elitek .

Elitek can cause a condition that affects the ability of your red blood cells to carry oxygen (methemoglobinemia). Do not restart Elitek if this effect occurs. Consult your doctor for more details.

Elitek can interfere with accurate measurements of uric acid in the blood, resulting in falsely low levels. Be sure to tell all lab personnel that you are using Elitek .

Elitek is used for:

Preventing high blood levels of uric acid from occurring in children with cancer (eg, leukemia, lymphoma, solid malignant tumors) who are about to receive cancer chemotherapy treatment.

Elitek is a urate-oxidase enzyme. When chemotherapy is given, cancer cells are destroyed, releasing large amounts of uric acid into the blood. Elitek works by allowing uric acid to be more easily removed from the body by the kidneys.

Do NOT use Elitek if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Elitek :

Some medical conditions may interact with Elitek . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Elitek . However, no specific interactions with Elitek are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Elitek may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Elitek :

Use Elitek as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Elitek .

Important safety information:

Possible side effects of Elitek :

All medicines may cause side effects, but many people have no, or minor, side effects.

Diarrhea; headache; mouth sores or ulcers; nausea; stomach pain; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blue or gray skin color; chest pain; chills; constipation; dark urine; fever; numbness or tingling of the skin; persistent sore throat; severe dizziness; shivering; weakness; yellowing of the eyes and skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Elitek is usually handled and stored by a health care provider. If you are using Elitek at home, store Elitek as directed by your pharmacist or health care provider. Keep Elitek out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Elitek . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

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Aloprim

Aloprim

Generic Name: allopurinol (Intravenous route)

al-oh-PURE-i-nol

Commonly used brand name(s):

Available Dosage Forms:

Therapeutic Class: Antigout

Pharmacologic Class: Xanthine Oxidase Inhibitor

Uses For Aloprim

Allopurinol is used to treat chronic gout (gouty arthritis). This condition is caused by too much uric acid in the blood.

This medicine works by causing less uric acid to be produced by the body. Allopurinol will not relieve a gout attack that has already started. Also, it does not cure gout, but it will help prevent gout attacks. However, it works only after you have been taking it regularly for a few months. Allopurinol will help prevent gout attacks only as long as you continue to take it.

Allopurinol is also used to prevent or treat other medical problems that may occur if too much uric acid is present in the body. These include certain kinds of kidney stones or other kidney problems.

Certain medicines or medical treatments can greatly increase the amount of uric acid in the body. This can cause gout or kidney problems in some people. Allopurinol is also used to prevent these problems, and can be given as either a tablet or an injection if necessary

Allopurinol is available only with your doctor’s prescription.

Before Using Aloprim

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

This medicine has been tested in children and, in effective doses, has not been shown to cause different side effects or problems than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of allopurinol in the elderly with use in other age groups.

Pregnancy

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

Proper Use of Aloprim

If this medicine upsets your stomach, it may be taken after meals. If stomach upset (indigestion, nausea, vomiting, diarrhea, or stomach pain) continues, check with your doctor.

In order for this medicine to help you, it must be taken regularly as ordered by your doctor.

To help prevent kidney stones while taking allopurinol, adults should drink at least 10 to 12 full glasses (8 ounces each) of fluids each day unless otherwise directed by their doctor. Check with the doctor about the amount of fluids that children should drink each day while receiving this medicine. Also, your doctor may want you to take another medicine to make your urine less acidic. It is important that you follow your doctor’s instructions very carefully.

For patients taking allopurinol for chronic gout:

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Aloprim

Your doctor should check your progress at regular visits. Blood tests may be needed to make sure that this medicine is working properly and is not causing unwanted effects.

Drinking too much alcohol may increase the amount of uric acid in the blood and lessen the effects of allopurinol. Therefore, people with gout and other people with too much uric acid in the body should be careful to limit the amount of alcohol they drink.

Taking too much vitamin C may make the urine more acidic and increase the possibility of kidney stones forming while you are taking allopurinol. Therefore, check with your doctor before you take vitamin C while taking this medicine.

Check with your doctor immediately:

Very rarely, these effects may be the first signs of a serious reaction to the medicine.

Allopurinol may cause some people to become drowsy or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert.

Aloprim Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Stop taking this medicine and get emergency help immediately if any of the following effects occur:

Check with your doctor as soon as possible if any of the following side effects occur:

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

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Uloric

Uloric

Generic Name: febuxostat (fe BUX oh stat)

What is Uloric?

Uloric is a prescription medicine called a xanthine oxidase inhibitor that reduces the production of uric acid in your body. Uric acid buildup can lead to gout or kidney stones.

Uloric is used to treat high blood concentrations of uric acid in patients with gout.

Uloric may also be used for other purposes not listed in this medication guide.

Important information about Uloric

You should not use Uloric if you are allergic to febuxostat, or if you are also being treated with azathioprine (Azasan, Imuran), mercaptopurine (Purinethol), or theophylline (Elixophyllin, TheoCap, Theochron, Uniphyl).

Before taking Uloric, tell your doctor if you have kidney disease, liver disease, diabetes, heart disease, or high blood pressure.

You may have an increase in gout symptom flares when you first start taking Uloric. For best results, keep taking the medication as directed. Your doctor may prescribe other gout medications for you to use during the first 6 months of treatment with Uloric.

Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using Uloric.

What should I discuss with my healthcare provider before taking Uloric?

You should not use Uloric if you are allergic to febuxostat, or if you are being treated with the any of the following medications:

azathioprine (Azasan, Imuran);

mercaptopurine (Purinethol); or

theophylline (Elixophyllin, TheoCap, Theochron, Uniphyl).

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before taking Uloric, tell your doctor if you have:

heart disease, high blood pressure; or

diabetes.

FDA pregnancy category C. It is not known whether Uloric is harmful to an unborn baby. Before taking Uloric, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether febuxostat passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Uloric?

Take Uloric exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose of Uloric to make sure you get the best results from this medication.

You may have an increase in gout symptom flares when you first start taking Uloric. For best results, keep taking the medication as directed. Your doctor may prescribe other gout medications for you to use during the first 6 months of treatment with Uloric.

To be sure this medication is helping your condition, your blood may need to be tested often. Do not miss any follow-up visits to your doctor.

Store Uloric at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of Uloric is not expected to produce life-threatening symptoms.

What should I avoid while taking Uloric?

Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using Uloric.

Uloric side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Uloric and call your doctor at once if you have any of these serious side effects:

chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;

sudden numbness or weakness, especially on one side of the body;

sudden headache, confusion, problems with vision, speech, or balance;

pale skin, easy bruising or bleeding;

hearing problems, ringing in your ears;

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

blood in your urine; or

urinating less than usual;

Less serious Uloric side effects may include:

fever, chills, body aches, flu symptoms;

upset stomach;

dry mouth, thirst;

blurred vision;

dizziness, spinning sensation;

joint pain, swelling, or stiffness;

muscle pain; or

mild skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Uloric?

There may be other drugs that can interact with Uloric. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Zyloprim

Zyloprim

Zyloprim is used for:

Treating gout. It is used to treat high uric acid levels in the blood or urine caused by certain types of cancer chemotherapy. It is also used to treat certain patients with calcium oxalate kidney stones and high amounts of uric acid in the urine. It may also be used for other conditions as determined by your doctor.

Zyloprim is a xanthine oxidase inhibitor. It works by lowering the body’s production of uric acid.

Do NOT use Zyloprim if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zyloprim :

Some medical conditions may interact with Zyloprim . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Zyloprim . Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Zyloprim may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Zyloprim :

Use Zyloprim as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Zyloprim .

Important safety information:

Possible side effects of Zyloprim :

All medicines may cause side effects, but many people have no, or minor, side effects.

Diarrhea; nausea.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in urine or painful urination; dark urine; fever, chills, or sore throat; irritation of the eyes; joint pain; loss of appetite; red, swollen, blistered, or peeling skin; stomach pain; unexplained weight loss; unusual bruising or bleeding; unusual muscle pain or weakness; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Store Zyloprim at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Zyloprim out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Zyloprim . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Zyloprim resources

Compare Zyloprim with other medications for the treatment of:

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