Archive for the ‘carbapenems’ Category

Primaxin IV

Primaxin IV

Primaxin IV is used for:

Treating serious infections caused by certain bacteria.

Primaxin IV is a carbapenem antibiotic. It kills bacteria by blocking growth of the bacteria’s cell wall.

Do NOT use Primaxin IV if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Primaxin IV :

Some medical conditions may interact with Primaxin IV . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Primaxin IV . Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Primaxin IV may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Primaxin IV :

Use Primaxin IV as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Primaxin IV .

Important safety information:

Possible side effects of Primaxin IV :

All medicines may cause side effects, but many people have no, or minor, side effects.

Mild diarrhea; nausea; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; breathing problems; chest pain; dark urine; decreased urination; fast or irregular heartbeat; fever, chills, or sore throat; hearing loss; joint pain or tenderness; mental or mood changes (eg, agitation, anxiety, confusion); numbness or tingling of the skin; pain, swelling, or redness at the injection site; red, swollen, blistered, or peeling skin; seizures; severe diarrhea; severe stomach cramps or pain; swelling of the hands or feet; tremors or abnormal muscle movements; shortness of breath; unusual bruising or bleeding; unusual tiredness or weakness; unusual vaginal odor or discharge; vein swelling or tenderness; white patches in the mouth; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Primaxin IV is usually handled and stored by a health care provider. If you are using Primaxin IV at home, store Primaxin IV as directed by your pharmacist or health care provider. Keep Primaxin IV out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Primaxin IV . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Primaxin IV resources

Compare Primaxin IV with other medications for the treatment of:

Primaxin IM

Primaxin IM

Primaxin IM is used for:

Treating serious infections of mild to moderate severity caused by certain bacteria.

Primaxin IM is a carbapenem antibiotic. It kills bacteria by blocking growth of the bacteria’s cell wall.

Do NOT use Primaxin IM if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Primaxin IM :

Some medical conditions may interact with Primaxin IM . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Primaxin IM . Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Primaxin IM may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Primaxin IM :

Use Primaxin IM as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Primaxin IM .

Important safety information:

Possible side effects of Primaxin IM :

All medicines may cause side effects, but many people have no, or minor, side effects.

Mild diarrhea; nausea; minor pain, swelling, or redness at the injection site; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; breathing problems; chest pain; dark urine; decreased urination; fast or irregular heartbeat; fever, chills, or sore throat; hearing loss; joint pain or tenderness; mental or mood changes (eg, agitation, anxiety, confusion); numbness or tingling of the skin; red, swollen, blistered, or peeling skin; seizures; severe diarrhea; severe stomach cramps or pain; swelling of the hands or feet; tremors or abnormal muscle movements; shortness of breath; swelling or redness at the injection site; unusual bruising or bleeding; unusual tiredness or weakness; unusual vaginal odor or discharge; vein swelling or tenderness; white patches in the mouth; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Primaxin IM is usually handled and stored by a health care provider. If you are using Primaxin IM at home, store Primaxin IM as directed by your pharmacist or health care provider. Keep Primaxin IM out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Primaxin IM . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Primaxin IM resources

Compare Primaxin IM with other medications for the treatment of:

Invanz

Invanz

Invanz is used for:

Treating moderate to severe infections caused by certain bacteria. It is also used to prevent infection after certain types of surgery. It may also be used for other conditions as determined by your doctor.

Invanz is an antibiotic. It works by killing sensitive bacteria.

Do NOT use Invanz if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Invanz :

Some medical conditions may interact with Invanz . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Invanz . Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Invanz may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Invanz :

Use Invanz as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Invanz .

Important safety information:

Possible side effects of Invanz :

All medicines may cause side effects, but many people have no, or minor, side effects.

Diarrhea; dizziness; headache; indigestion; nausea; sleeplessness; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; breathing problems; chest pain; fast heartbeat; fever, chills, or sore throat; mental or mood changes (eg, agitation, anxiety, confusion); pain, swelling, or redness at the injection site; seizures; severe or persistent diarrhea; severe stomach cramps or pain; swelling of hands or feet; tremors or abnormal muscle movements; unusual vaginal odor or discharge; white patches in the mouth.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Invanz is usually handled and stored by a health care provider. If you are using Invanz at home, store Invanz as directed by your pharmacist or health care provider. Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Invanz out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Invanz . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Invanz resources

Compare Invanz with other medications for the treatment of:

Merrem

Merrem

Generic Name: meropenem (mer oh PEH nem)

What is Merrem?

Merrem is an antibiotic. It fights bacteria in the body.

Merrem is used in the treatment of infections of the abdomen, such as appendicitis and peritonitis, bacterial meningitis (infection of the lining of the brain), and skin infections.

Merrem may also be used for purposes other than those listed here.

Important information about Merrem

Do not take Merrem without first talking to your doctor if you have an allergy to meropenem, imipenem (Primaxin), a penicillin antibiotic, or a cephalosporin antibiotic.

Before taking Merrem

Do not take Merrem without first talking to your doctor if you have an allergy to meropenem, imipenem (Primaxin), a penicillin antibiotic, or a cephalosporin antibiotic.

Before taking Merrem, talk to your doctor if you have

a head injury or brain tumor;

epilepsy or a seizure disorder; or

You may not be able to use Merrem, or you may require a dosage adjustment or special monitoring during treatment.

Merrem is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not use Merrem without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether Merrem passes into breast milk. Do not take Merrem without first talking to your doctor if you are breast-feeding a baby.

How should I take Merrem?

Merrem will be administered as an intravenous (into a vein) injection by a healthcare provider.

If you are using Merrem at home, your healthcare provider will give you detailed instructions regarding preparation, administration, and storage of the medication.

It is important to take Merrem regularly to get the most benefit.

Take all of the Merrem that has been prescribed for you, even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.

Your doctor may want you to have blood tests or other medical evaluations during treatment with Merrem to monitor progress and side effects.

What happens if I miss a dose?

Since Merrem is usually administered by a healthcare provider, missing a dose is not likely to occur.

What happens if I overdose?

Seek emergency medical attention if an overdose of Merrem is suspected.

Symptoms of a Merrem overdose are not known.

What should I avoid while taking Merrem?

There are no restrictions on food, beverages, or activities during treatment with Merrem unless otherwise directed by your doctor.

Merrem side effects

If you experience a rare but serious side effects, stop taking Merrem and seek emergency medical attention or contact your doctor immediately:

allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives)

seizures;

severe or watery diarrhea;

a skin rash;

unusual tiredness or weakness; or

unusual bleeding or bruising.

Other less serious side effects may be more likely to occur. Continue to use Merrem and talk to your doctor if you experience:

nausea or vomiting;

diarrhea or constipation;

headache; or

soreness, redness, or mild swelling at the injection site.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Merrem?

Talk to your doctor and pharmacist before taking Merrem if you are taking any other prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Doribax

Doribax

Generic Name: doripenem (dor i PEN em)

What is Doribax?

Doribax is an antibiotic that fights serious infections caused by bacteria.

Doribax is used to treat severe infections of the stomach, bladder, or kidneys.

Doribax may also be used for other purposes not listed in this medication guide.

Important information about Doribax

You should not use Doribax if you are allergic to doripenem or imipenem (Primaxin), or a history of allergy to penicillin antibiotics such as Amoxil, Augmentin, Omnipen, Principen, Dycill, Dynapen, Bactocill, Beepen-VK, Ledercillin VK, Pen-V, Pfizerpen, Veetids, and others.

Before using Doribax, tell your doctor if you are allergic to any drugs, or if you have kidney disease or a seizure disorder.

Before using Doribax, tell your doctor if you are using valproic acid (Depakene) or probenecid (Benemid).

You may be shown how to use your medicine at home. Do not self-inject this medicine if you do not fully understand how to mix the medicine, give the injection and properly dispose of needles, IV tubing, and other items used in giving the medicine.

Call your doctor at once if you have serious side effects such as diarrhea that is watery or bloody, trouble breathing, easy bruising or bleeding, seizure (convulsions), or fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.

Before receiving Doribax

You should not use Doribax if you are allergic to doripenem or imipenem (Primaxin), or a history of allergy to penicillin antibiotics such as Amoxil, Augmentin, Omnipen, Principen, Dycill, Dynapen, Bactocill, Beepen-VK, Ledercillin VK, Pen-V, Pfizerpen, Veetids, and others.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Doribax:

kidney disease; or

epilepsy or other seizure disorder.

FDA pregnancy category B. Doribax is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether doripenem passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How is Doribax given?

Doribax is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting. The medicine must be given slowly through an IV infusion, and can take at least 1 hour to complete.

Doribax is usually given for 5 days to 2 weeks, depending on the condition being treated. You may be switched to an oral (pill form) antibiotic after the first few days of receiving a doripenem injection.

Use Doribax for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. This medicine will not treat a viral infection such as the common cold or flu.

You may be shown how to use your medicine at home. Do not self-inject this medicine if you do not fully understand how to mix the medicine, give the injection and properly dispose of needles, IV tubing, and other items used in giving the medicine.

Doribax is a powder that must be mixed with a liquid (diluent). Do not mix the medicine or draw your dose into a syringe until you are ready to inject the medicine. Ask your pharmacist if you have questions about mixing the Doribax injection.

After mixing Doribax with the diluent, keep it in a refrigerator. Keep from freezing, and use the mixture within 24 hours.

What happens if I miss a dose?

Call your doctor for instructions if you miss a dose of Doribax.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a Doribax overdose are not known.

What should I avoid while receiving Doribax?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

Doribax side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Doribax: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

diarrhea that is watery or bloody;

trouble breathing;

pale skin, easy bruising or bleeding;

seizure (convulsions); or

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.

Less serious Doribax side effects may include:

pain, swelling, or redness where the medicine was injected;

mild nausea;

headache;

mild skin rash or itching;

white patches or sores inside your mouth; or

vaginal itching or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Doribax?

Before using Doribax, tell your doctor if you are using any of the following medications:

valproic acid (Depakene); or

probenecid (Benemid).

This list is not complete and there may be other drugs that can interact with Doribax. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

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