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Archive for the ‘nicotinic acid derivatives’ Category

Trecator-SC

Posted by admin on November 2nd, 2009

Trecator-SC

Generic Name: ethionamide (e thye on AM ide)

What is Trecator-SC (ethionamide)?

Ethionamide is an antibiotic. It prevents the growth of bacteria in your body.

Ethionamide is used to treat tuberculosis (TB).

Ethionamide may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Trecator-SC (ethionamide)?

Take all of the ethionamide that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.

Ethionamide may cause stomach upset, a loss of appetite, a metallic taste in your mouth, or excessive salivation (mouth watering). Notify your doctor if these side effects are persistent or severe.

Who should not take Trecator-SC (ethionamide)?

Before taking this medication, tell your doctor if you

have ever had an allergic reaction to ethionamide;

have liver disease; or

have diabetes mellitus.

You may not be able to take ethionamide, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

It is not known whether ethionamide will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. It is also not known whether ethionamide will harm a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take Trecator-SC (ethionamide)?

Take ethionamide exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass (8 ounces) of water.

Ethionamide can be taken with or without food. Taking ethionamide with food may decrease stomach upset.

Take all of the ethionamide that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.

Ethionamide is usually combined with one or more other tuberculosis medicines.

Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of an ethionamide overdose are unknown.

What should I avoid while taking Trecator-SC (ethionamide)?

There are no restrictions on foods, beverages, or activities during treatment with ethionamide unless your doctor directs otherwise.

Trecator-SC (ethionamide) side effects

If you experience any of the following serious side effects, stop taking ethionamide and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

yellow skin or eyes;

dark urine;

numbness or tingling in your hands or feet;

seizures;

blurred or double vision; or

confusion or abnormal behavior.

Other, less serious side effects may be more likely to occur. Continue to take ethionamide and talk to your doctor if you experience

nausea, vomiting, or loss of appetite;

a metallic taste in your mouth;

excessive salivation;

diarrhea;

unusual fatigue or weakness;

headache;

mild dizziness;

tremors (shaking); or

a rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Trecator-SC (ethionamide)?

The risk of seizures may be increased when ethionamide is used in combination with cycloserine (Seromycin) or isoniazid (Nydrazid). Special monitoring may be necessary if you are taking a combination of these medicines.

Drugs other than those listed here may also interact with ethionamide. Talk to your doctor and pharmacist before taking or using any other prescription or over-the-counter medicines.

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Trecator

Posted by admin on November 2nd, 2009

Trecator

Trecator is used for:

Treating tuberculosis (TB) infections in combination with other medicines. It may also be used for other conditions as determined by your doctor.

Trecator is an antibacterial agent. It works by inhibiting or stopping the growth of TB cells, which results in cell death.

Do NOT use Trecator if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Trecator :

Some medical conditions may interact with Trecator . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Trecator . However, no specific interactions with Trecator are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Trecator may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Trecator :

Use Trecator as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Trecator .

Important safety information:

Possible side effects of Trecator :

All medicines may cause side effects, but many people have no, or minor, side effects.

Diarrhea; dizziness; drowsiness; headache; increased salivation; loss of appetite; metallic taste; mouth sores; nausea; restlessness; stomach pain; vomiting; weight loss.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in sense of smell; depression; easy bruising or bleeding; low blood sugar (eg, increased heartbeat, headache, chills, sweating, tremor, increased hunger, changes in vision, nervousness, weakness, dizziness, drowsiness, fainting); tingling of hands or feet; vision changes (eg, loss of vision); yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Store Trecator at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Keep Trecator out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Trecator . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Trecator resources

Compare Trecator with other medications for the treatment of:

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Nydrazid

Posted by admin on November 2nd, 2009

Nydrazid

Nydrazid may cause severe and sometimes fatal liver problems (eg, hepatitis). The risk of liver problems is greater in patients older than 35 years old. It may also be increased by daily use of alcohol, long-term liver problems, or unsanitary injectable drug use. Women, especially those who are black, are Hispanic, or have just had a baby, may also be at increased risk. Hepatitis can develop at any time during treatment, but usually occurs during the first 3 months. Your doctor will monitor your liver function and discuss your progress every month.

Contact your doctor right away if you develop unusual fatigue, weakness or fever that lasts longer than 3 days, general feeling of discomfort, loss of appetite, nausea, vomiting, numbness or tingling of the hands or feet, dark urine, yellowing of the skin or eyes, or stomach pain or tenderness. Your doctor may decide to slowly restart isoniazid after these symptoms disappear and lab tests return to normal.

Patients with active liver problems should not use Nydrazid .

Nydrazid is used for:

Treating or preventing tuberculosis (TB). If you are using Nydrazid to treat TB, it should always be used along with another medicine.

Nydrazid is an antibacterial. It works by killing TB organisms.

Do NOT use Nydrazid if:

Contact your doctor or health care provider right away if any of these apply to you.

Before using Nydrazid :

Some medical conditions may interact with Nydrazid . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Nydrazid . Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Nydrazid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Nydrazid :

Use Nydrazid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Nydrazid .

Important safety information:

Possible side effects of Nydrazid :

All medicines may cause side effects, but many people have no, or minor, side effects.

Mild stomach upset.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; chills or fever; dark urine; general feeling of discomfort; increased thirst or urination; joint pain or swelling; loss of appetite; memory problems; mental or mood changes; nausea; seizures; stomach pain or tenderness; symptoms of low vitamin B

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (

Nydrazid is usually handled and stored by a health care provider. If you are using Nydrazid at home, store Nydrazid as directed by your pharmacist or health care provider. Keep Nydrazid out of the reach of children and away from pets.

General information:

This information is a summary only. It does not contain all information about Nydrazid . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

More Nydrazid resources

Compare Nydrazid with other medications for the treatment of:

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